• Nonhyperkeratotic, nonhypertrophic actinic keratoses on the face or scalp in immunocompetent adults:
    • 5% cream: apply twice per week at bedtime *16/52
      • Max: 1 pkt/application
      • Limit treatment area to 25cm2 on face or scalp
    • 75% cream: apply at bedtime*2/52, off for 2 weeks
      • Max: 2 actuations/application
  • External genital and perianal warts/condyloma acuminate (1st line agent):
    • 5% cream: apply three times per week at bedtime
      • Max 16 weeks
      • Wash with mild soap and water after 6-10 hours of application
      • Apply until total clearance or max duration
    • 75% cream: apply OD at bedtime
      • Max 8 weeks
      • Wash with mild soap and water after 8 hours of application
      • Apply until total clearance or max duration
  • Superficial basal cell carcinoma:
    • 5% cream: Apply 5 times/week at bedtime *6/52
    • Limit tumor area to 2 cm diameter
    • Not for use on face, hands, feet
  • Antiviral-resistant genital HSV in immunocompromised patients:
    • 5% cream: Apply 3 times/week at bedtime
    • Wash with mild soap and water after 8 hours of application
  • Cream:
    • 3.75%
    • 5%
  • Avoid use in or on lips, nostrils or eyes
  • Non-occlusive dressings such as cotton gauze/underwear may be used in management of skin reactions in external genital warts

Its exact mechanism of action unknown but thought to stimulates Toll-like receptor 7, modifying immune responses

  • Local inflammatory reaction
  • Application site reaction
  • Headache
  • Influenza-like symptoms
  • Anorexia
  • Dizziness
  • Herpes simplex
  • Pain
  • Chest pain
  • Diarrhea
  • Lymphadenopathy
  • Dyspepsia
  • Hypersensitivity to components
  • Pregnancy

None remarkable

                          Drug Status

Availability Prescription only
Pregnancy Category C
Breastfeeding Use with caution
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Aldara 5% w/w Sachet 12’s iNova Pharma Phillips Therapeutics
Imidara 5% w/w Cream 4g Biopharma Ltd Biopharma Ltd
Imiquad 5% w/w Sachet 3’s Glenmark Pharma Glenmark Pharma