- Nonhyperkeratotic, nonhypertrophic actinic keratoses on the face or scalp in immunocompetent adults:
- 5% cream: apply twice per week at bedtime *16/52
- Max: 1 pkt/application
- Limit treatment area to 25cm2 on face or scalp
- 5% cream: apply twice per week at bedtime *16/52
-
- 75% cream: apply at bedtime*2/52, off for 2 weeks
- Max: 2 actuations/application
- 75% cream: apply at bedtime*2/52, off for 2 weeks
- External genital and perianal warts/condyloma acuminate (1st line agent):
- 5% cream: apply three times per week at bedtime
- Max 16 weeks
- Wash with mild soap and water after 6-10 hours of application
- Apply until total clearance or max duration
- 5% cream: apply three times per week at bedtime
-
- 75% cream: apply OD at bedtime
- Max 8 weeks
- Wash with mild soap and water after 8 hours of application
- Apply until total clearance or max duration
- 75% cream: apply OD at bedtime
- Superficial basal cell carcinoma:
- 5% cream: Apply 5 times/week at bedtime *6/52
- Limit tumor area to 2 cm diameter
- Not for use on face, hands, feet
- Antiviral-resistant genital HSV in immunocompromised patients:
- 5% cream: Apply 3 times/week at bedtime
- Wash with mild soap and water after 8 hours of application
- Cream:
- 3.75%
- 5%
- Avoid use in or on lips, nostrils or eyes
- Non-occlusive dressings such as cotton gauze/underwear may be used in management of skin reactions in external genital warts
Its exact mechanism of action unknown but thought to stimulates Toll-like receptor 7, modifying immune responses
- Local inflammatory reaction
- Application site reaction
- Headache
- Influenza-like symptoms
- Anorexia
- Dizziness
- Herpes simplex
- Pain
- Chest pain
- Diarrhea
- Lymphadenopathy
- Dyspepsia
- Hypersensitivity to components
- Pregnancy
None remarkable
Drug Status
Availability | Prescription only |
Pregnancy | Category C |
Breastfeeding | Use with caution |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Aldara | 5% w/w | Sachet | 12’s | iNova Pharma | Phillips Therapeutics |
Imidara | 5% w/w | Cream | 4g | Biopharma Ltd | Biopharma Ltd |
Imiquad | 5% w/w | Sachet | 3’s | Glenmark Pharma | Glenmark Pharma |