- Acne vulgaris:
- Apply OD nocte
- Apply sparingly to affected area after thoroughly washing the face
Cream: 5% w/w
- Best used at night
- Avoid contact with the eyes, lips, mucous membranes and mouth
- Avoid excessive sun exposure and use sunscreen
- Stop use if irritation becomes severe
- Concomitant administration with sulfone products (sulfacetamide or dapsone) may result in temporary discoloration (orange/yellow) of facial hair and skin
Exact mechanism is unknown but it is thought to elicit a keratolytic and desquamative effect which may contribute to its efficacy
It is effective in vitro against Propionibacterium acnes found in sebaceous follicles and comedones
- Xeroderma
- Erythema
- Burning
- Pruritus
- Peeling
- Application site edema
- Photosensitivity
- Hypersensitivity to class/compound
- Topical hydroquinone
- Topical dapsone
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Category C |
| Breastfeeding | Can be used |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Aknekot | 5% w/w | Gel | 20g | Biopharma Ltd | Biopharma Ltd |
| Pernex AC | 5% w/w | Gel | 20g | Oaknet Healthcare | Pharma Specialities |
| Pritti | 5% w/w | Gel | 20g | Hiral Labs | Hazella Ltd |