- Acne vulgaris:
- Apply every night at bedtime
- Reassess if no improvement after 12 weeks
Cream: 0.1% w/w + 1% w/w
- Apply thin film to entire face and other affected areas of the skin every evening after washing gently with non-medicated soap.
Adapalene: Retinoid. It binds to nuclear retinoic acid receptors, modulating cellular differentiation, keratinization and inflammatory processes all of which represent important features in the pathology of acne vulgaris.
Clindamycin: Lincomycin; It inhibits bacteria protein synthesis at the ribosomal level by binding to the 50S ribosomal subunit and affecting the process of peptide chain initiation. It inhibits growth of Propionibacterium acnes.
- Xeroderma
- Scaling
- Erythema
- Burning
- Stinging
- Skin discomfort
- Pruritus
- Photosensitivity
- Abdominal pain
- GI disturbances
- Hypersensitivity to components
- History of ulcerative colitis
- History of antibiotic-associated colitis
- Products containing sulfur, resorcinol and salicyclic acid
Drug Status
| Availability | Prescription only |
| Pregnancy | Category C |
| Breastfeeding | Unknown; use with caution |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Adacin | 0.1% w/w + 1% w/w | Gel | 15g | Ajanta Pharma | Harley’s Ltd |
| Blemish | 0.1% w/w + 1% w/w | Gel | 15g | Kusum Healthcare | Zawadi Healthcare |
| Clindap | 0.1% + 1% w/w | Cream | 15g | Galaxy Pharma | Galaxy Pharma |
| Klenzit-C | 0.1% w/w + 1% w/w | Ointment | 15g | Glenmark Pharma | Glenmark Pharma |