- Neuromuscular blockade:
- Induction:
- Adults: IV 0.3-1.1mg/kg/dose *1 OR IM 3-4mg/kg/dose *1.
- Children: IV 1-2mg/kg/dose *1 OR IM 2.5-4mg/kg/dose *1
- Consider premed with atropine
- Induction:
-
- Maintenance:
- Adults: IV 0.04-0.07mg/kg/dose every 5-10min PRN OR5-10 mg/min
- Children: IV 0.3-0.6mg/kg/dose every 5-10min PRN
- Maintenance:
- Rapid sequence intubation (Off-label):
- IV 1-2mg/kg/dose *1
- Consider premed with atropine
Injection: 50mg/mL
- Drug may be diluted to 1mg/mL or 2mg/mL in 5% Dextrose or 0.9% Sodium Chloride
- To avoid distress to patient, do not administer drug before unconsciousness has been induced
- Atropine is used prior to reduce occurrence of bradyarrhythmias
- Total dose for IM administration should not exceed 150mg
- IM effect can be seen in 2-3 minutes
- IM injections should be made deeply, preferably high into deltoid muscle
Neuromuscular blocker
It depolarizes motor endplate causing sustained flaccid skeletal muscle paralysis
- Postop myalgia
- Muscle fasciculation
- Jaw rigidity
- Elevated IOP
- Hypertension
- Hypotension
- Bradycardia
- Tachycardia
- Sialorrhea
- Rash
- Hypersensitivity to components/class
- Malignant hyperthermia history
- Myopathy history
- Major acute trauma
- Major acute burn
- Acute extensive muscular denervation
- Acute upper motor neuron injury
- Increased IOP
WARNING
Acute rhabdomyolysis with hyperkalemia followed by ventricular dysrhythmias, cardiac arrest and death has occurred after administration of succinylcholine to apparently healthy pediatric patients who were subsequently found to have undiagnosed skeletal muscle myopathy.
None restricted
Drug Status
Availability | Prescription only |
Pregnancy | Category C; Weigh risk vs benefit |
Breastfeeding | Weigh risk vs benefit |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Sucol | 50mg/mL | Injection | 10’s | Neon Labs | Ripple Pharma |
Suxamed | 50mg/mL | Injection | 1’s | Medisel Kenya | Medisel Kenya |
Suxamethonium | 100mg/2mL | Injection | 1’s | Galaxy Pharma | Galaxy Pharma |
Suxamethonium Chloride | 100mg/2mL | Injection | 10’s | Macarthys Labs | Laborex Kenya |
Suxamethonium Chloride | 50mg/mL | Injection | 5’s | Rotexmedica GMBH | Nairobi Pharma |
Suxamethonium Fresenius | 100mg/2mL | Injection | 10’s | Fresenius Kabi | Surgipharm Ltd |