• Treatment or prevention of bronchospasm in patients with reversible obstructive airway disease:
    • Nebulizer solution:
      • Adult: 5mg BD/TDS PRN OR 1.25-5mg every 4-8 hour PRN for quick relief
      • <2 years (off-label): 2-0.6 mg/kg/day divided every 4-6 hour
      • 2-12 years and <15 kg: 5mg/0.5mL (0.5 % solution) every 6-8 hour
        • Not to exceed 10mg (4 vials)/24 hours
      • 2-12 years and >15 kg: 1 vial (2.5mg/3mL) every 6-8 hours
        • Max 10mg (4 vials)/24 hours
      • >12 years: 5mg (1 vial) every 6-8 hours PRN
        • Max 10mg/24 hours
    • Aerosol metered-dose inhaler:
      • Adult: PO 180mcg (2 puffs) inhaled every 4-6 hour. Max 12 inhalations/24 hour
      • ≥4 years: 90-180mcg (1-2 puffs) inhaled every 4-6 hours
    • Tablet:
      • <6 years: PO 0.3-0.6mg/kg/day divided TDS.
        • Max 12mg/day
    • 6-12 years: PO 2mg every TDS/QID.
      • Can be gradually increased to ≤24 mg/day in divided doses
    • Adult and ≥12 years: PO 2-4mg TDS/QID.
      • Max 32 mg/day
    • Suspension:
      • 2-6 years: Initially PO 0.1mg (0.25mL)/kg TDS.
        • Max 2mg (5mL) TDS
        • If necessary, may be increased to 0.2 mg/kg every 8 hours, not to exceed 4mg (10mL) every 8 hours
      • 6-14 years: PO 2mg (5mL) TDS/QID
        • May be gradually increased to ≤24 mg/day in divided doses
      • >14 years: PO 2-4mg TDS/QID
        • Max 32 mg/day
  • Acute or severe bronchospasm:
    • Nebulizer solution: 5-5mg every 20min for 3 doses; follow with 2.5-10mg every 1-4 hours PRN or 10-15 min by continuous nebulization
    • Metered-dose inhaler: 4-8 puffs inhaled every 20min for up to 4 hours and then every 1-4 hours PRN
  • Prevention of exercise-induced bronchospasm:
    • Metered-dose inhaler:
      • Adults and >4 years: 180mcg (2 puffs) inhaled 15-30 min before exercise
  • Tablet:
    • 2mg
    • 4mg
  • Suspension:
    • 2mg/5mL
  • Nebulizing solution:
    • 100mcg/dose
  • Injection:
    •  0.5mg/mL

Should not be chewed, crushed or mixed with food

Direct-acting sympathomimetic.

Selective beta2 receptor agonist with some beta1 activity. It relaxes bronchial smooth muscle with little effect on heart rate

  • Throat irritation
  • URI symptoms
  • Cough
  • Bad taste
  • Tremor
  • Dizziness
  • Nervousness
  • Nausea
  • Vomiting
  • Headache
  • Palpitations
  • Tachycardia
  • Pain
  • Hyperlactatemia
  • Vomiting
  • Skeletal muscle tremors
  • Palpitations
  • Muscle cramps
  • Tachycardia
  • Headache
  • Peripheral vasodilation
  • Paradoxical bronchospasm
  • Angioedema
  • Severe emotional disturbances
  • Resistance after prolonged use
  • Hypersensitivity to class/components
  • Hypersensitivity to milk proteins
  • Cisapride
  • Dronedarone
  • Saquinavir
  • Thioridazine

                                   Drug Status

Availability Prescription or OTC by Pharmacist
Pregnancy Weigh risk vs benefit
Breastfeeding Can be used
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Asthadin 2mg/5mL Suspension 60mL, 100mL Dinlas Pharma Dinlas Pharma
Asthalin 100mcg Inhalation 200D Cipla Ltd Imperial Managed
Azmasol HFA 100mcg Inhalation 200D Beximco Pharma Madawa Pharma
Bonair HFA 100mcg Inhalation 200D Midascare Pharma Prunus Pharma
Brodil HFA 100mcg Inhalation 200D Advanced Chemical Radiance Pharma
Butin 2mg/5mL Suspension 60mL, 100mL Sphinx Pharma Sphinx Pharma
Derihaler 100mcg Inhalation 200D Cadila Healthcare Cadila Healthcare
Lastmol 2mg/5mL Suspension 60mL, 100mL Laboratory & Allied Laboratory & Allied
Lastmol 4mg Tablet 100’s, 1000’s Laboratory & Allied Laboratory & Allied
Medisalant 100mcg Inhalation 200D Medisel Kenya Medisel Kenya
Nebzmart S 2.5mg Inhalation solution 10’s Glenmark Pharma Glenmark Pharma
Sabulin 4mg Tablet 100’s, 1000’s Dawa Ltd Dawa Ltd
Sabulin 2mg/5mL Suspension 60mL, 100mL Dawa Ltd Dawa Ltd
Salamol 100mcg Inhalation 200D KNVM Medicare KNVM Medicare
Salbucort 100mcg Inhalation 200D Hetero Labs Unisel Ltd
Salbumed 2mg/5mL Suspension 60mL, 100mL Medivet Products Medivet Products
Salbumol 2mg/5mL Suspension 100mL Regal Pharma Regal Pharma
Salbut 2mg/5mL Suspension 100mL Cosmos Ltd Cosmos Ltd
Salbut 4mg Tablet 100’s Cosmos Ltd Cosmos Ltd
Salbutamol 100mcg/dose Inhalation 200D Sandoz GMBH Novartis Kenya
Salfil 4mg Tablet 1000’s Beta Healthcare Beta Healthcare
Sultolin HFA 100mcg Inhalation 200D Square Pharma Ace Pharma
Salol 2mg/5mL Suspension 100mL Biopharma Ltd Biopharma Ltd
Salol 4mg Tablet 100’s Biopharma Ltd Biopharma Ltd
Tabusol 2mg/5mL Suspension 100mL Benmed Pharma Benmed Pharma
Tavent 100mcg Inhalation 200D Crown Healthcare Crown Healthcare
Venteze 2mg/5mL Suspension 100mL Beta Healthcare Beta Healthcare
Ventil 2mg/5mL Suspension 60mL, 100mL Biodeal Labs Biodeal Labs
Ventil 4mg Tablet 100’s, 1000’s Biodeal Labs Biodeal Labs
Ventolin 4mg Tablet 240’s GSK Ltd GSK Ltd
Ventolin 0.5mg/mL Injection 5’s GSK Ltd GSK Ltd
Ventolin 5mg/mL Suspension 100mL GSK Ltd GSK Ltd
Ventolin Evohaler 100mcg Inhaler 200D GSK Ltd GSK Ltd
Ventolin Respirator Solution 5mg/mL Nebulizer solution 10mL GSK Ltd GSK Ltd
Ventolin Rotacaps 200mcg Rotacap 100’s GSK Ltd GSK Ltd
Ventomac 100mcg Inhalation 1’s Macleods Pharma Sai Pharma
Ventosal 2mg/5mL Suspension 100mL Elys Chemicals Elys Chemicals
Ventosal 4mg Tablet 100’s, 1000’s Elys Chemicals Elys Chemicals
Ventosal-4 4mg Tablet 1000’s Elys Chemicals Elys Chemicals