Neomycin/ Nystatin/ Polymyxin B

• Pessary:
  • 100,000 IU/35,000 IU/35,000 IU

• Used at night at bedtime
• Wear cotton underwear.
• Avoid vaginal showers.
• Avoid the use of tampons during the treatment.
• Do not discontinue the treatment during menstruation periods.
• The sexual partner may also be treated

Neomycin: aminoglycoside antibiotic. It works by inhibiting bacterial protein synthesis leading to its bactericidal effect on gram-negative bacteria.

Nystatin: antifungal. It allows the destruction of some microscopic fungus blocks their growth

Polymyxin B: polypeptide antibiotic. It disrupts the outer cell membrane of Gram negative bacteria, binds and neutralizes lipopolysaccharide and inhibits respiration of Gram-negative bacterial cells

• Vaginal burning/itching
• Gritty sensation in the vagina
• Stomach pain
• Nausea
• Discharge

• Hypersensitivity to components
• Use of latex diaphragms or condoms
• Spermicidal products (local contraceptives)
• Kidney failure

• Spermicidal products (local contraceptives)