• Vaginal infections due to Candida albicans, Trichomonas vaginalis or mixed infections caused by two or more of these species:
    • Vaginally 1 pessary OD *3/7
  • Pessary:
    • 100mg/300mg/200mg
  • Used at night at bedtime
  • Used preferably away from the menstrual cycle

Lidocaine: Local amide anesthetic. It facilitates an anesthetic effect by preventing pain signals from propagating to the brain and by aborting theirgeneration.

Tinidazole: Antiprotozoal. The nitro group of tinidazole is reduced in Trichomonas by a ferredoxin-mediated electron transport system. The free nitro radical generated as a result of this reduction is believed to be responsible for the antiprotozoal activity.  These toxic free radicals covalently bind to DNA, causing DNA damage and leading to cell death.

Tioconazole: Synthetic antifungal agent with a high in-vitro efficacy to yeast and fungi. It is also used in some bacterial infections. It alters the permeability of the fungal cell membrane by inhibition of the ergosterol synthesis which leads to increase of cellular permeability and therefore to leakage of intracellular phosphorus compounds and potassium across the cell membrane.

  • Genital edema
  • Erythema
  • Burning sensation
  • Pruritus
  • Erythematous rash
  • Lower extremity swelling
  • Vaginal bleeding
  • Vulvovaginal burning
  • Urinary burning
  • Hypersensitivity to components
  • First trimester
  • Breastfeeding
  • Neurologic disorders
  • Current or history of blood dyscrasia
  • Alcohol

                                   Drug Status

Availability Prescription only
Pregnancy Contraindicated in 1st trimester
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Ovurol 100mg/300mg/200mg Pessary 3’s Exeltis Phillips Therapeutics