- Mild oropharyngeal candidiasis:
- 6 months-2 years: PO 1.25mL 4 times daily *7-14 days
- >2 yrs and adult: PO 2.5mL 4 times daily *7-14 days
Oral gel:
- 2% w/w
- The oral gel should be kept in the mouth for 2-3 minutes and then swallowed, or in young children, applied to the tongue and inside of each cheek.
Imidazole antifungal
It binds to lanosterol 14 alpha-demethylase, inhibiting ergosterol synthesis and disrupting fungal cell membrane integrity.
- Local irritation
- Diarrhea
- Headache
- Nausea
- Taste disturbance
- Vomiting
- Xerostomia
- Cough
- Fatigue
- Anemia
- Abdominal pain
- URI
- Pruritus
- <6 months old
- Hypersensitivity to drug or ingredient
- Hepatic impairment
- Antivitamin K agents (risk of hemorrhage)
- Glibenclamide (increased hypoglycaemic effect)
- Phenytoin (increased plasma concentration of phenytoin)
Drug Status
| Availability | Prescription or OTC by pharmacist |
| Pregnancy | Can be used |
| Breastfeeding | Can be used |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Daktarin Oral Gel | 2% w/w | Oral Gel | 40g | Janssen Pharma | Janssen Pharma |
| Domogel | 2% w/w | Oral Gel | 40g | Cosmos Ltd | Cosmos Ltd |
| Laeotarin Oral Gel | 2% w/w | Oral Gel | 40g | Laboratory & Allied | Laboratory & Allied |
| Micona | 2% w/w | Oral Gel | 40g | Centaur Pharma | Sai Pharma |
| Miconaz Oral Gel | 2% w/w | Oral Gel | 20g | Medical Union | Harley’s Ltd |
| Oromucoral | 2% w/w | Oral Gel | 40g | Galentic Pharma | Avacare Kenya |