• Depression:
    • PO 20mg OD AM.
    • May increase dose gradually after several weeks by 20mg/day; not to exceed 80mg /day
  • Obsessive-compulsive disorder:
    • PO 20mg OD AM.
    • May increase dose gradually after several weeks by 20mg/day; not to exceed 80mg /day
  • Bulimia nervosa:
    • PO 60mg OD AM
    • Dose may be titrated to 60mg/day over several days
  • Panic disorder:
    • Initially PO 10 mg OD *1/7, THEN 20 mg OD AM.
    • Max 60mg/day
  • Premenstrual dysphoric disorder:
    • PO 20mg OD
    • Max 80mg/day. No proven benefit with doses >20mg/day

Capsules: 20mg

  • Best taken in the morning.
  • Taper dose to discontinue.
  • Discontinue if seizure develops.

Selective serotonin reuptake inhibitor.

  • Insomnia
  • Nausea
  • Headache
  • Asthenia
  • Diarrhoea
  • Somnolence
  • Nervousness
  • Tremor
  • Dry mouth
  • Dyspepsia
  • Flu syndrome
  • Palpitations
  • Dizziness
  • Impotence
  • Hypersensitivity to excipients
  • Breastfeeding
  • Severe renal failure
  • Children (increased suicidal tendencies)
  • Manic phase of depression
  • MAO inhibitor use within 14 days
  • Linezolid
  • Phenelzine
  • Quinidine

                                   Drug Status

Availability Prescription only
Pregnancy Category C
Breastfeeding  Contraindicated
Schedule Controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Deprozet 20mg Capsule 30’s Cosmos Ltd Cosmos Ltd
Fludac 20mg Capsule 20’s Cadila Pharm Cadila Pharm
Flunil 20mg Capsule 30’s Intas Pharma Accord Healthcare
Fluxil 20mg Capsule 30’s Delorbis Pharma Europa Healthcare
Modipran 20mg Capsule 100’s Beximco Pharma Madawa Pharma
Prodep 20mg Capsule 60’s Sun Pharma Sun Pharma