- Nondepolarizing neuromuscular blockade reversal:
- Rocuronium or vecuronium moderate blockade:
- Adults and >2 years: IV 2mg/kg/dose *1
- For patients undergoing surgery with spontaneous recovery reaching reappearance of 2nd twitch to train-of-four
- Rocuronium or vecuronium moderate blockade:
-
- Rocuronium or vecuronium moderate blockade:
- Adults and >2 years: IV 4mg/kg/dose *1
- For patients undergoing surgery with spontaneous twitch response recovery reaching 1-2 post-tetanic counts and no twitch response to train-of-four
- Rocuronium or vecuronium moderate blockade:
-
- Rocuronium immediate reversal:
- IV 16mg/kg/dose *1
- For patients undergoing surgery requiring reversal after rocuronium 1.2mg/kg/dose *1
- Rocuronium immediate reversal:
Injection: 100mg/mL
It can make hormonal birth control less effective therefore use a non-hormonal back-up birth control to prevent pregnancy.
Selective relaxant binding agent; Anesthesia adjunct
It forms a complex with neuromuscular blocker, reducing binding availability to nicotinic cholingeric receptors
- Pain
- Nausea
- Vomiting
- Hypotension
- Headache
- Abdominal pain
- Extremity pain
- Dizziness
- Fever
- Bradycardia
- Eye disorders (peds patients)
- Insomnia
- Hypoesthesia
- Anxiety
- Myalgia
- Increased CK
- Xerostomia
- Known hypersensitivity to drug or any of its components
- CrCl <30
None restricted
Drug Status
| Availability | Prescription only |
| Pregnancy | Category B2; Weigh risk vs benefit |
| Breastfeeding | Weigh risk vs benefit |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Bridion | 200mg/2mL | Injection | 1’s, 20’s | MSD Ltd | Imperial Managed |