- Reduce the risk of preterm birth:
- IM 250mg every week until 37 week gestation or delivery
- Initiate between the 16th and 20th week of gestation
Injection: 250mg/mL
- Slow IM injection in upper outer quadrant of the gluteus maximus
- Rotate injection site to alternate side from previous week
Synthetic progestin
Exact mechanism of action unknown
- Injection site reaction
- Urticaria
- Premature labor
- Pre-eclampsia
- Pruritus
- Nausea
- Diabetes mellitus
- Diarrhea
- Fluid retention
- Injection site cellulitis
- Thromboembolism or history of thromboembolism
- Breast cancer or history of breast cancer
- Hormone sensitive cancer or history of hormone sensitive cancer
- Undiagnosed abnormal vaginal bleeding unrelated to pregnancy
- Cholestatic jaundice of pregnancy
- Liver tumors or active liver disease
- Uncontrolled hypertension
- Hypersensitivity to castor oil or hydroxyprogesterone caproate
None restricted
Drug Status
Availability | Prescription only |
Pregnancy | Indicated |
Breastfeeding | Not indicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Primolut Depot | 250mg/mL | Injection | 1’s | Bayer Schering | Bayer Schering |