- Inhibition of lactation:
- 1mg single dose
- Given on day 1 of postpartum
- Suppression of established lactation:
- 0.25mg BD twice a week
- Hyperprolactinemia either idiopathic or from pituitary adenoma:
- 0.25mg twice a week
- Can be increased every 4 weeks by 0.25mg twice a week based on prolactin levels
- Max: 1mg twice a week
Tablet: 0.5mg
- Lowest effective dose is used
- May discontinue after normal prolactin levels are maintained for 6 months
- Preferably taken with meals
Dopamine receptor agonist
It has high affinity for dopamine D2 receptors. When these receptors are stimulated, they inhibit prolactin release.
- Nausea
- Headache
- Dizziness
- Constipation
- Asthenia
- Fatigue
- Abdominal pain
- Somnolence
- Postural hypotension
- Depression
- Dyspepsia
- Vomiting
- Anxiety
- Hypersensitivity to class/components
- Hypersensitivity to ergot derivatives
- Cardiac valvular fibrosis
- Pericardial fibrosis
- Pulmonary fibrosis
- Retroperitoneal fibrosis
- Uncontrolled or gestational hypertension
- Breastfeeding
- Nitroglycerin
- Sumatriptan
- Zolmitriptan
- Glyceryl nitrate
- Phenothiazines
- Thioxanthines
- Metoclopramide
- Macrolide antibiotics
Drug Status
| Availability | Prescription only |
| Pregnancy | Category B |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Caberline | 0.5mg | Tablet | 4’s | Sun Pharma | Sun Pharma |
| Cabgolin | 0.5mg | Tablet | 4’s | Relax Biotech | Krishna Chemists |