• Chronic Immune Thrombocytopenia (ITP):
    • 50mg OD
    • Max: 75mg/day
  • Chronic Hepatitis C-associated thrombocytopenia:
    • 25mg OD
    • Increase by 25mg every 2 weeks PRN
  • Severe aplastic anemia:
    • 1st line treatment: 150mg OD *6/12
    • Refractory disease: 50mg OD
  • Tablet:
    • 25mg
    • 50mg

Take 1 hour before or 2 hour after meals

Hematopoietic Growth Factor

It binds and activates thrombopoietin (TPO) receptors on hematopoietic cells, increasing platelet production (TPO receptor agonist) through proliferation & differentiation of megakaryocytes from bone marrow progenitor cells

  • URI
  • Headache
  • Nausea & vomiting
  • Diarrhea
  • Cough
  • Fever
  • Abdominal pain
  • Vomiting
  • Oropharyngeal pain
  • Myalgia
  • UTI
  • Cataracts
  • Fatigue
  • Increased ALT/AST
  • Musculoskeletal pain
  • Influenza
  • Rash
  • Paresthesia
  • Hyperbilirubinemia
  • Xerostomia
  • Alopecia
  • Dizziness
  • Decreased appetite
  • Peripheral edema
  • Pruritus
  • Insomnia
  • Skin discoloration
  • Hypersensitivity to class/components
  • Myelodysplastic syndrome
  • ALT/AST >6x ULN (first-line treatment in severe aplastic anemia use)
  • Breastfeeding

WARNING:

  • Use with interferon and ribavirin may increase risk of hepatic decompensation in chronic hepatitis C patients
  • Increased risk of severe and potentially life-threatening hepatotoxicity
  • Grazoprevir

                          Drug Status

Availability Prescription only
Pregnancy Category C
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Revolade 25mg Tablet 28’s Novartis Kenya Novartis Kenya
Revolade 50mg Tablet 28’s Novartis Kenya Novartis Kenya