- Treatment of gout:
- PO 1mg x1, then 1 hour later 0.5mg x1
- Do not repeat within 3 days
- Prophylaxis of gout:
- PO 0.5mg OD/BD
- Wait 12 hours after acute gout flare treatment before resuming prophylaxis
Tablet: 0.5mg
To be taken without regard to meals.
Antigout agent
It inhibits microtubule polymerization preventing activation, degranulation and migration of neutrophils which is related to the symptoms of gout.
- Diarrhoea
- Nausea
- Cramping
- Abdominal pain
- Vomiting
- Pharyngolaryngeal pain
- Headache
- BM suppression
- Renal and hepatic impairment
- Cardiac disorders
- Hypersensitivity to class/compound
- Atazanavir
- Chloramphenicol
- Clarithromycin
- Cyclosporine
- Itraconazole
- Ketoconazole
- Lopinavir/ritonavir
- Mifepristone
- Ritonavir
- Voriconazole
Drug Status
| Availability | Prescription only |
| Pregnancy | Category C |
| Breastfeeding | Avoid breastfeeding 2-4 hours after dose |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Goutnil | 0.5mg | Tablet | 20’s | Inga Labs | Sai Pharma |
| Kolzine | 0.5mg | Tablet | 100’s | Metro Pharma | Metro Pharma |