• For ocular inflammation with superficial bacterial infection or risk:
    • Adults & children >2 years: 1-2 gtt to affected eye(s) every 4-6 hour
      • May use hourly in severe disease

OR 

    • Adults & children >2 years: Apply ribbon (0.5 inch) to affected eye(s) in conjunctival sac every 4-6 hours or as adjunct to suspension

Eye drops/ointment: 1mg + 3500 IU + 6000 IU

  • Remove contact lenses before applying the eye drops and wait until 10 min before inserting contact lenses.
  • Discard 4 weeks after opening bottle
  • Eye drops should be used before eye ointments
  • If using more than 1 eye drop, they should be administered at least 5 minutes apart

Neomycin: Aminoglycoside; it binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis

Polymyxin B: Polypeptide; it increases cell wall permeability thereby causing intracellular products to leak

Dexamethasone: Steroid; it prevents/reduces irritation & swelling by suppressing normal immune response, decreasing inflammatory mediators and reverses capillary permeability

  • Ocular burning
  • Ocular stinging
  • Ocular irritation
  • Elevated IOP
  • Ocular viral infection
  • Ocular mycobacterial infection
  • Ocular fungal infection
  • Corneal abrasion
  • Abrupt withdrawal (long-term use)

None restricted

                          Drug Status

Availability Prescription only
Pregnancy Contraindicated in long term use
Breastfeeding Can be used
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Polytrol 0.1% + 3,500 IU + 6,000 IU Eye Drops 5mL ATCO Labs Globe Pharmacy
Maxitrol 0.1% + 3,500 IU + 6,000 IU Eye Drops 5mL Novartis Pharma Pan Pharma
Maxitrol 0.1% + 3,500 IU + 6,000 IU Eye Ointment 3.5g Novartis Pharma Pan Pharma