- Open-angle glaucoma, closed-angle glaucoma, secondary glaucoma:
- 125mg-250mg BD/QID
- 125mg-250mg BD/QID
- Altitude sickness prevention:
- 125mg BD
- Start 24-48 hours before ascent and continue for 48 hours at high altitude or longer, to control symptoms if necessary
- Altitude sickness treatment:
- 250mg BD
- 250mg BD
- CHF-associated edema:
- 250-375mg OD AM
- 250-375mg OD AM
- Drug-induced edema:
- 250-375 mg OD
- 250-375 mg OD
- Absence and generalized seizure disorders:
- 375-1000mg/day divided BD/QID
- 250mg OD if with other anticonvulsants
Tablet: 250mg
- To be taken in the morning
Carbonic anhydrase inhibitor
It decreases the rate of aqueous humor formation thereby decreasing intraocular pressure. It also inhibits H+ ion excretion in renal tubule, increasing sodium, potassium, bicarbonate and water excretion and producing alkaline dieresis.
It also works by inhibiting carbonic anhydrase in CNS, which in turn decreases abnormal and excessive discharge from the CNS neurons.
- Fatigue
- Malaise
- Taste changes
- Anorexia
- Nausea
- Vomiting
- Paresthesia
- Diarrhea
- Polyuria
- Electrolyte disorders
- Tinnitus
- Hypokalemia
- Hyponatremia
- Hyperchloremic acidosis
- Hypersensitivity to acetazolamide or sulphur
- Liver disease/ cirrhosis
- Severe renal dysfunction
- Long term use in non-congestive angle-closure glaucoma
- Metoclopramide
- Quinidine
- Amphetamine
Drug Status
Availability | Prescription only |
Pregnancy | Category C |
Breastfeeding | Contraindicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Acetamox | 250mg | Tablet | 30’s | Sai Pharma | Sai Pharma |
Diamox | 250mg | Tablet | 100’s | Aspen Pharma | Omaera Pharma |