• Pain in knee osteoarthritis:
    • 2mL intra-articularly once weekly *3-5 doses
  • Injection:
    • 10mg/mL
    • 8mg/mL
  • Remove synovial fluid or effusion prior to each injection

Intra-articular agent

It works by maintaining synovial fluid viscosity and supports articular cartilage shock absorption

  • Injection site pain
  • Headache
  • Injection site reaction
  • Rash
  • Joint swelling
  • Joint effusion
  • Arthralgia
  • Pruritus
  • Hypersensitivity to components
  • Concurrent ammonium salt skin disinfectant use
  • Intrathecal use
  • Extra-articular injection use
  • Knee joint infection or history
  • Injection site infection or history
  • Skin disease at injection site

None remarkable

                          Drug Status

Availability Prescription only
Pregnancy Weigh risk vs benefit
Breastfeeding Not recommended
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Hyorth 20mg/2mL Pre-filled Injection 1’s Virchow Healthcare Surgipharm Ltd
Hyorth XL 8mg/mL Pre-filled Injection 1’s Virchow Healthcare Surgipharm Ltd