- GERD:
- Adults: PO 20mg OD *4/52
- 1 month-1: 1mg/kg per day
- > 1 year (10-20kg): 10-20mg OD *4/52
- >2 years (20kg): PO 20-40mg *4/52
- Gastric ulcer:
- PO 40mg OD *4-8 weeks
- PO 40mg OD *4-8 weeks
- Duodenal ulcer:
- PO 20mg OD *4-8 weeks
- PO 20mg OD *4-8 weeks
- Erosive esophagitis:
- PO 20mg OD *4-8 weeks
- 1 month-1: PO 1mg/kg per day
- > 1 year (10-20kg): PO 10-20mg OD *4-8 weeks
- >2 years (20kg): PO 20-40mg *4-8 weeks
- NSAID-ass. gastric ulcer prophylaxis:
- PO 20-40mg OD
- PO 20-40mg OD
- H.pylori infection as part of a regimen:
- Adults: PO 20mg BD
- Children 15-31kg: PO 10mg BD *1/52
- Children 31-40kg: PO 20mg BD *1/52
- IV 40mg used where oral dosing is inappropriate
Capsule: 20mg, 40mg
Tablet: 10mg
Injection: 40mg/vial
- To be given 30 minutes before meals.
Proton pump inhibitor.
It inhibits the H+/K+-exchanging ATPase (proton pump) in gastric parietal cells thereby inhibiting gastric acid secretion.
- Headache
- Abdominal pain
- Diarrhoea
- Nausea
- Vomiting
- Flatulence
- Dizziness
- Vit B12 deficiency with long term use
- URTI
- Acid regurgitation
- Hypersensitivity to components
- Diazepam
- Warfarin
- Phenytoin
- Cyclosporine
- Disulfiram
- Ketoconazole
- Ampicillin esters
- Iron salts
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Safety not established. Contraindicated |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Belifax | 20mg | Capsule | 14’s | Pharmathen Pharma | Goodman Agencies |
| Dawapraz | 20mg | Capsule | 30’s, 100’s | Dawa Ltd | Dawa Ltd |
| Gasec | 20mg | Capsule | 14’s | Acino Pharma | Goodman Agencies |
| Lomizol | 20mg | Capsule | 20’s | Benmed Pharma | Benmed Pharma |
| Losec Mups | 10mg | Tablet | 14’s, 28’s | AstraZeneca | AstraZeneca |
| Losec Mups | 20mg | Tablet | 14’s | AstraZeneca | AstraZeneca |
| Ocid | 20mg | Capsule | 100’s | Cadila Healthcare | Cadila Healthcare |
| OM | 20mg | Capsule | 100’s | Laboratory & Allied | Laboratory & Allied |
| Omapez | 20mg | Capsule | 100’s | PSM Pharma | PSM Pharma |
| Omecer | 20mg | Capsule | 14’s | PDH Pharma | Pharmaken Ltd |
| Omecos | 20mg | Capsule | 100’s | Cosmos Ltd | Cosmos Ltd |
| Omeflux | 20mg | Capsule | 30’s, 100’s | Biodeal Labs | Biodeal Labs |
| Omegut | 40mg | Injection | 1’s, 5’s | Popular Pharma | Madawa Pharma |
| Omemark | 40mg | Injection | 1’s | Marksans Pharma | Sai Pharma |
| Omenix | 40mg | Injection | 1’s | Incepta Pharma | Radiance Pharma |
| Omepraglobe | 20mg | Capsule | 100’s | Globela Pharma | Globela Pharma |
| Omfil | 20mg | Capsule | 100’s | Fourrts Labs | Sai Pharma |
| Omicap | 20 mg | Capsule | 100’s | Micro Labs | Micro Labs |
| Omis | 20mg | Capsule | 100’s | National Pharmacy | National Pharmacy |
| Omlink | 20mg | Capsule | 100’s | Lincoln Pharma C/O Medox Pharma | Medox Pharma |
| Ommed | 20mg | Capsule | 100’s | Medico Remedies | Harley’s Ltd |
| Ompra | 20mg | Capsule | 100’s | Zawadi Healthcare | Zawadi Healthcare |
| Onpraz | 20mg | Capsule | 100’s | Crown Healthcare | Crown Healthcare |
| Poraz | 20mg | Capsule | 100’s | Medley Pharma | Zawadi Healthcare |
| Proceptin | 20 mg | Capsule | 30’s | Beximco Pharma | Madawa Pharma |
| Prohibin | 20 mg | Capsule | 100’s | Leben Labs | Unisel Ltd |
| Risek | 20mg | Capsule | 14’s | Getz Pharma | Surgipharm Ltd |
| Risek | 40mg | Capsule | 14’s | Getz Pharma | Surgipharm Ltd |
| Risek | 40mg | Injection | 1’s | Getz Pharma | Surgipharm Ltd |
| Seclo | 20mg | Capsule | 100’s | Square Pharma | Ace Pharma |
| Seclo | 40mg | Capsule | 30’s | Square Pharma | Ace Pharma |
| Ulzol | 20mg | Capsule | 20’s | Universal Corporation | Universal Corporation |
| Zep | 20mg | Capsule | 100’s | Asence Pharma | Medisel Kenya |
| Zocid | 20mg | Capsule | 100’s | Zest Pharma | Synermed Pharma |
| Zosec | 20mg | Capsule | 10’s | Centaur Pharma | Lazor Pharma |