• Diarrhea/flatulence:
    • 6-8 years: PO 1 tab *1, then 1/2 tab after each loose stool
      • Max: 2 tabs/24 hours
    • 9-11 years: PO 1 tab *1, then 1/2 tab after each loose stool
      • Max: 3 tabs/24 hours
    • 12 years and older: PO 2 tabs *1, then 1 tab after each loose stool
      • Max: 4 tabs/24 hours

Tablet: 2mg/125mg

None remarkable

Loperamide; it binds to the opiate receptor in the gut wall reducing propulsive peristalsis and increasing intestinal transit time

Simethicone: changes surface tension of gas bubbles, causing collapse of foam bubbles thereby allowing easier passage

  • Abdominal cramps
  • Constipation
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Nausea
  • Hypersensitivity to class/components
  • Abdominal pain without diarrhea
  • Bloody diarrhea (loperamide)
  • GI obstruction (simethicone)
  • Infectious diarrhea (loperamide)
  • Intestinal perforation (simethicone)
  • Pseudomembranous colitis (loperamide)
  • Patients <2 years old (loperamide)
  • Acute ulcerative colitis
  • Pimozide
  • Potassium salts
  • Thioridazine
  • Ziprasidone

                          Drug Status

Availability OTC
Pregnancy Category C
Breastfeeding Use with caution
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Loflatil 2mg/125mg Tablet 10’s Kusum Healthcare Zawadi Healthcare