• GERD with erosive esophagitis:
    • PO 20mg/40mg OD *4-8 weeks
  • GERD without erosive esophagitis:
    • PO 20mg OD * 4/52
  • H.pylori eradication:
    • PO 40mg OD * 10/7 in combination therapy with amoxicillin 1g BD *10/7, clarithromycin 500mg BD * 10/7.
  • Frequent heartburn:
    • PO 20mg OD*14/7
  • Risk reduction on long term NSAID therapy:
    • PO 20mg OD up to 6 months.
  • Zollinger-Ellison syndrome:
    • PO 60mg BD
  • Prevention of post-endoscopy gastric/duodenal ulcer re-bleeding:
    • IV 80mg *1, then 8mg/hr *72hrs
  • Tablet/Capsule:
    • 20mg
    • 40mg
  • Injection/infusion:
    • 40mg/vial

Food delays and decreases absorption therefore taken 30minutes before meals

Proton pump inhibitor.

It binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion. Effects occur after 1 hour. S-isomer of omeprazole.

  • Headache
  • Diarrhoea
  • Abdominal pain
  • Vomiting
  • Flatulence
  • Nausea
  • Vomiting.

Hypersensitivity to PPIs.

  • Vitamin B12
  • Nelfinavir
  • Atazanavir
  • Clopidogrel

                                 Drug Status

Availability Prescription or OTC by Pharmacist
Pregnancy Can be used
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Esofag 40mg Tablet 30’s Micro Labs Micro Labs
Esofag 20mg Tablet 30’s Micro Labs Micro Labs
Esofast 20mg Tablet 10’s Innocia Lifesciences Wessex Pharma
Esofast 40mg Tablet 10’s Innocia Lifesciences Wessex Pharma
Esoflux 20mg Capsule 10’s, 40’s The ACME Labs Highridge Pharma
Esoflux 40mg Capsule 30’s The ACME Labs Highridge Pharma
Esofred 20mg Capsule 30’s Crown Healthcare Crown Healthcare
Esofred 40mg Capsule 30’s Crown Healthcare Crown Healthcare
Esoglax 20mg Tablet 30’s Galaxy Pharma Galaxy Pharma
Esoglax 40mg Tablet 30’s Galaxy Pharma Galaxy Pharma
Esoglax 40mg Injection 1’s Galaxy Pharma Galaxy Pharma
Esomac 20mg Tablet 28’s Cipla Ltd Imperial Managed
Esomac 40mg Tablet 14’s Cipla Ltd Imperial Managed
Esome 20 mg Capsule 14’s Getz Pharma Surgipharm Ltd
Esome 40mg Injection 14’s Getz Pharma Surgipharm Ltd
Esome 40mg Injection 1’s Getz Pharma Surgipharm Ltd
Es-Omecos 40mg Tablet 30’s Cosmos Ltd Cosmos Ltd
Esomezol 20mg Capsule 30’s Inventia Healthcare Europa Healthcare
Esomezol 40mg Capsule 30’s Inventia Healthcare Europa Healthcare
Esonea 40mg Tablet 30’s Relax Biotech Radiance Pharma
Esonea 40mg Injection 1’s Relax Biotech Radiance Pharma
Esonium 20mg Tablet 30’s Galaxy Pharma Galaxy Pharma
Esonium 40mg Tablet 30’s Galaxy Pharma Galaxy Pharma
Esonium 40mg Injection 1’s Galaxy Pharma Galaxy Pharma
Esonix 40mg Injection 1’s Radiance Pharma Radiance Pharma
Esop 40mg Injection 1’s Zest Pharma Synermed Pharma
Esop 40mg Tablet 30’s Zest Pharma Synermed Pharma
Esopra 20mg Tablet 10’s PSA International Avacare Kenya
Esopra 40mg Tablet 10’s PSA International Avacare Kenya
Esopraz 20mg Tablet 30’s Crown Healthcare Crown Healthcare
Esopraz 40mg Tablet 30’s Crown Healthcare Crown Healthcare
Esoral 20mg Tablet 20’s Eskayef Ltd Umoja Pharma
Esoral 40mg Tablet 20’s Eskayef Ltd Umoja Pharma
Esose 20mg Tablet 10’s, 30’s Glenmark Pharma Glenmark Pharma
Esose 40mg Tablet 10’s, 30’s Glenmark Pharma Glenmark Pharma
Esose 40mg Injection 1’s Glenmark Pharma Glenmark Pharma
Esostar 40mg Tablet 30’s Medistar Pharma Medistar Pharma
Esostar 20mg Tablet 30’s Medistar Pharma Medistar Pharma
Esoxium 20mg Tablet 30’s Signature Healthcare Signature Healthcare
Esoxium 40mg Tablet 10’s Signature Healthcare Signature Healthcare
Espra 40mg Capsule 14’s CCL Pharma Harley’s Ltd
Esta 20mg Tablet 14’s Questa Care C/O Surgilinks Ltd Surgilinks Ltd
Esta 40mg Injection 1’s Surgilinks Ltd C/O Mac Heal Labs Surgilinks Ltd
Eszed 40mg Injection 1’s Zawadi Healthcare Zawadi Healthcare
Exium 20mg Capsule 30’s Radiant Pharma Radiant Pharma
Exium 40mg Capsule 30’s Radiant Pharma Radiant Pharma
Ezo 20mg Tablet 10’s Ind-Swift Ltd Ind-Swift Ltd
Ezo 40mg Tablet 10’s Ind-Swift Ltd Ind-Swift Ltd
GastroIV 40mg Injection 1’s Krishna Chemists Krishna Chemists
Gastrotab 20mg Tablet 10’s Krishna Chemists Krishna Chemists
Gastrotab 40mg Tablet 10’s Krishna Chemists Krishna Chemists
Izra 20mg Tablet 30’s Unichem Labs Europa Healthcare
Izra 40mg Tablet 30’s Unichem Labs Europa Healthcare
Nexiole 40mg Tablet 10’s Pro MedPharma Pro MedPharma
Nexiole 20mg Tablet 10’s Pro MedPharma Pro MedPharma
Nexium 20mg Tablet 14’s, 28’s AstraZeneca AstraZeneca
Nexium 40mg Tablet 14’s AstraZeneca AstraZeneca
Nexium 10mg Sachet 28’s AstraZeneca AstraZeneca
Nexium 40mg Injection 10’s AstraZeneca AstraZeneca
Nexpro 40mg Tablet 50’s Torrent Pharma C/O Medox Medox Pharma
Nexpro 40mg Injection 1’s Torrent Pharma C/O Medox Medox Pharma
Prazonac 20mg Capsule 30’s Curis Lifesciences Nacc Med Pharma
Prazonac 40mg Capsule 30’s Curis Lifesciences Nacc Med Pharma
Progut 40mg Injection 1’s Nextgen Pharma Nextgen Pharma
Protas 20mg Tablet 30’s, 100’s Square Pharma Ace Pharma
Protas 40mg Tablet 30’s, 100’s Square Pharma Ace Pharma
Protas 40mg Injection 1’s Square Pharma Ace Pharma
Rayzium 40mg Tablet 30’s Biodeal Labs Biodeal Labs
Rayzium 20mg Tablet 30’s Biodeal Labs Biodeal Labs
Sergel 20mg Capsule 30’s Healthcare Pharma Nextgen Pharma
Sergel 40mg Capsule 30’s Healthcare Pharma Nextgen Pharma
Sergel 40mg Injection 1’s Healthcare Pharma Nextgen Pharma
Sompraz 40mg Tablet 30’s Sun Pharma Sun Pharma
Sompraz 20mg Tablet 30’s Sun Pharma Sun Pharma
Sompraz 40mg Injection 1’s Sun Pharma Sun Pharma
Stulcer 40mg Tablet 30’s Gufic Stridden Biopharma Europa Healthcare
Stulcer 20mg Tablet 30’s Gufic Stridden Biopharma Europa Healthcare
Stulcer 40mg Injection 1’s Gufic Stridden Biopharma Europa Healthcare
Zomep ES 20mg Tablet 30’s Zawadi Healthcare Zawadi Healthcare
Zomep ES 40mg Tablet 30’s Zawadi Healthcare Zawadi Healthcare