• Psychosis:
    • IM 12.5-25mg every 3-6 weeks
    • Increase by 12.5-25mg every 3-6 weeks
    • Max: 100mg/dose

Injection: 25mg/mL

  • Not to be given IV

Phenothiazine

It selectively antagonizes dopamine D2 receptors

  • Anticholinergic effects
  • Sedation
  • Weight gain
  • Erectile dysfunction
  • Oligomenorrhea/ amenorrhea
  • Extrapyramidal symptoms
  • Nausea
  • Anorexia
  • Dyspepsia
  • Headache
  • Peripheral edema
  • Depression
  • Leukopenia
  • Hyperprolactinemia
  • Gynecomastia
  • Galactorrhea
  • Impotence
  • Hypersensitivity to class/components
  • Comatose patients
  • Subcortical brain damage
  • Severe CNS depression
  • Severe respiratory depression
  • Severe bone marrow depression
  • Blood dyscrasia
  • Hepatotoxicity

WARNING

Patients with dementia-related psychosis are at increased risk for death

  • Saquinavir
  • Yohimbe
  • Potassium salts
  • Ibutilide
  • Indapamide
  • Metrizamide
  • Pentamidine
  • Pimozide
  • Procainamide
  • Quinidine
  • Sotalol
  • Amisulpride
  • Disopyramide

                          Drug Status

Availability Prescription only
Pregnancy Category C
Breastfeeding Contraindicated
Schedule Controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Fluanxol 0.5mg Tablet 100’s Janssen Pharma Phillips Therapeutics
Fluanxol 3mg Tablet 100’s Janssen Pharma Phillips Therapeutics
Fluanxol Depot 20mg/mL Injection 1’s Janssen Pharma Phillips Therapeutics
Fluanxol Depot 40mg/2mL Injection 1’s Janssen Pharma Phillips Therapeutics