• Hypertension:
    • 1 tab OD
  • Tablet:
    • 80mg/12.5mg
    • 160mg/12.5mg
  • It can be used as initial treatment if BP unlikely to be controlled by a single agent
  • Best taken in the morning due to the diuresis effect of hydrochlorothiazide (peaks in 4 hours)

Valsartan: Angiotensin II receptor (ARB) blocker

Hydrochlorothiazide: thiazide diuretic

  • Increased BUN ≥50%
  • Dizziness
  • Postural hypotension
  • Diarrhoea
  • Arthralgia
  • Fatigue
  • Back pain
  • Dizziness
  • Hyperkalemia
  • Hyperglycemia
  • Glycosuria
  • Hyperuricaemia
  • Hyponatremia
  • Anorexia
  • Impotence
  • Postural hypotension
  • Gastric irritation
  • Nausea
  • Vomiting
  • Hypokalemia
  • Orthostatic hypotension
  • Hypersensitivity to component or sulfonamides
  • Severe renal failure
  • Severe hepatic failure
  • Hypokalemia
  • Anuria
  • Pregnancy; causes oligohydramnios in foetus resulting in foetus injury or death. Withdraw as soon as pregnancy is detected
  • ACEIs
  • Lithium
  • Amikacin
  • Erythromycin
  • Halofantrine
  • Pentamidine
  • Terfenadine
  • Mannitol

                                   Drug Status

Availability Prescription only
Pregnancy Category D
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Co-Diovan 160mg/12.5mg Tablet 28’s Novartis Pharma Novartis Kenya
Co-Diovan 80mg/12.5mg Tablet 28’s Novartis Pharma Novartis Kenya
Cotroval 80mg/12.5mg Tablet 28’s Delorbis Pharma Europa Healthcare
Cotroval 160mg/12.5mg Tablet 28’s Delorbis Pharma Europa Healthcare
Starval HCT 80 80mg/12.5mg Tablet 30’s Sun Pharma Sun Pharma
Starval HCT 80 160mg/25mg Tablet 30’s Sun Pharma Sun Pharma