• Mild to moderate hypertension:
    • PO 1 tab OD
    • Max: 10mg ramipril/ 50mg hydrochlorothiazide

Tablet:

  • 5mg/12.5mg
  • 5mg/25mg
  • Can be taken with or without food

Ramipril: ACE Inhibitor.  It acts primarily on the suppression of the plasma renin-angiotensin aldosterone system thus decreasing plasma angiotensin II concentration, leading to decreased vasopressor activity and reduced aldosterone secretion.

Hydrochlorothiazide: Thiazide diuretic. It inhibits sodium reabsorption in distal renal tubules, resulting in increased excretion of water and of sodium, potassium and hydrogen ions.

  • Nausea
  • Indigestion
  • Taste change
  • Diarrhea
  • Stomach pain
  • Headache
  • Dizziness
  • Weakness
  • Glucose intolerance
  • Increased uric acid level in blood
  • Increased blood lipid level
  • Electrolyte imbalance
  • Cough
  • Decreased blood pressure
  • Tickling
  • Nutritional disorders
  • Worsening of diabetes
  • Hypotension
  • Hypersensitivity to drug/ingredients
  • History of angioedema
  • Electrolyte imbalances
  • Hepatic problems
  • Pregnancy
  • Breastfeeding
  • Aliskiren
  • Allopurinol
  • Amiloride
  • Sacubitril/valsartan

                                   Drug Status

Availability Prescription only
Pregnancy Contraindicated
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Tritazide 5mg/12.5mg Tablet 28’s Sanofi-Aventis Ressourcethica Kenya
Tritazide 5mg/25mg Tablet 28’s Sanofi-Aventis Ressourcethica Kenya