- Hypertension in patients already controlled with perindopril and amlodipine at the same dose level.
- 1 tab OD
Perindopril arginine/amlodipine besylate: 5mg/5mg, 10mg/5mg, 10mg/10mg, 5mg/10mg
NOT suitable as an initial therapy
Perindopril arginine: ACE inhibitor
Amlodipine besylate: Dihydropyridine, Calcium channel blocker
- Peripheral edema
- Cough
- Headache
- Dizziness
- Asthenia
- Mood swings
- Cramps
- Dry mouth
- Blood test abnormalities
- GI disorders
- Hypotension
- Hypersensitivity to components/class
- History of angioedema with previous ACEI treatment
- Pregnancy
- CrCl <30
- Severe hypotension
- Unstable angina pectoris
- High grade aortic stenosis
- Shock
- Diuretics
- Sympathomimetics
- Gold
- NSAIDs
- Antidiabetic drugs
- Dantrolene
- Rifampicin
- Carbamazepine
- Phenytoin
- Fosphenytoin
- Primidone
- Itraconazole
- Ketoconazole
- Beta blockers
- Corticosteroids
- Alpha blockers
- Tricyclic antidepressants
- Antipsychotics
- Anesthetics
- Immunosuppressive agents
Coveram (Servier)
Drug Status
| Availability | Prescription only |
| Pregnancy | Category D |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |