• Hypertension:
    • Initially PO 25-100mg OD
    • Usual range 50-100mg/day
    • May be increased at intervals of 1 week or longer
    • Max 400mg/day
  • Angina: Initially PO 100mg/day
    • May be increased at intervals of 1 week or longer
    • Max 400mg/day
  • Congestive heart failure:
    • Initially PO 25mg OD increased every 2 weeks PRN
    • Target dose: 200mg/day
  • Migraine(Off-label):
    • PO 50-200mg OD
    • Max: 200mg/day
    • Taper dose over 1-2 weeks to discontinue
  • Tablet:
    • 25mg
    • 50mg
    • 100mg
  • Taken with or without food

Beta blocker

Cardio-selective for beta 1 receptors at low doses, with little or no effect on beta 2 receptors

  • Fatigue
  • Dizziness
  • Diarrhea
  • Pruritus
  • Rash
  • Depression
  • Dyspnea
  • Bradycardia
  • Sleep disturbance
  • Nightmares
  • Sinus bradycardia
  • HR <45 BPM (MI use)
  • Sick sinus syndrome (patients without pacemaker)
  • 2nd-3rd degree AV block (patients without pacemaker)
  • AV block with PR interval >0.24sec (MI use)
  • Decompensated heart failure
  • Moderate-severe heart failure (MI use)
  • SBP <100 (MI use)
  • Cardiogenic shock
  • Pheochromocytoma (beta blocker monotherapy use)
  • Severe PVD
  • Isocarboxazid

                          Drug Status

Availability Prescription only
Pregnancy Category C
Breastfeeding Use with caution
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Betaloc ZOK 50mg Tablet 30’s AstraZeneca AstraZeneca
Betaloc ZOK 25mg Tablet 14’s AstraZeneca AstraZeneca
Betaloc ZOK 100mg Tablet 30’s AstraZeneca AstraZeneca
Met XL 25mg Tablet 30’s Ajanta Pharma Harley’s Ltd
Met XL 50mg Tablet 30’s Ajanta Pharma Harley’s Ltd
Met XL 100mg Tablet 30’s Ajanta Pharma Harley’s Ltd
Metpure XL 25mg Tablet 30’s Emcure Pharma Lazor Pharma
Metpure XL 50mg Tablet 30’s Emcure Pharma Lazor Pharma
Metpure XL 100mg Tablet 30’s Emcure Pharma Lazor Pharma
Revelol XL 25mg Tablet 30’s IPCA Labs Sai Pharma
Revelol XL 50mg Tablet 30’s IPCA Labs Sai Pharma