- Hypertension
Initiallly: 250mg BD/TDS * 2/7.
Adjusted in intervals of not less than 2 days until an adequate response is achieved. Maximum recommended daily dosage: 3g
Tablet: 250mg
Starting dose or increasing dose should be done in the evening with the larger dose taken in the evening due to its sedative effect.
Centrally acting antihypertensive. Alpha-2 receptor agonist.
It causes a decrease in sympathetic outflow and decreased blood pressure.
- Sedation during initial therapy or when dose is increased.
- Orthostatic hypotension
- Peripheral edema
- Bone marrow depression
- Leucopenia
- Drug-related fever
- Granulocytopenia
- Hyperprolactinemia
- Decreased libido
- Gynecomastia
- Myocarditis
- Pericarditis
- Pancreatitis
- Diarrhoea
- Sore or “black” tongue
- Hypersensitivity to components
- Phaeochromocytoma
- Hepatic failure
- Depression
- MAOI
- Alcohol
- Bromocriptine
- Lithium
- Sympathomimetics
- CNS depressants
- Promethazine
Drug Status
| Availability | Prescription only |
| Pregnancy | Category A; Safe to use |
| Breastfeeding | Safe to use |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Aldomet | 250mg | Tablet | 30’s | Aspen Global Incorporated | Beta Healthcare |
| Aldomet | 500mg | Tablet | 30’s | Aspen Global Incorporated | Beta Healthcare |
| Biodopa | 250mg | Tablet | 100’s, 1000’s | Biodeal Labs | Biodeal Labs |
| Dopamac | 250mg | Tablet | 100’s | Macleods Pharma | Sai Pharma |
| Hydopa | 250mg | Tablet | 100’s | Laboratory & Allied | Laboratory & Allied |
| Medopress | 250mg | Tablet | 100’s | Cosmos Ltd | Cosmos Ltd |
| Methyldopa | 250mg | Tablet | 100’s, 1000’s | Medopharm C/O Medox | Medox Pharma |