- Hypertension:
- PO 12.5 -50mg daily alone or in combination with other antihypertensives.
- Edema:
- PO 25-100 mg OD/BD. Not to exceed 200 mg/day.
- Diabetes insipidus:
- PO 100mg daily
Tablet:
- 25mg
- 50mg
Best taken in the morning due to its diuresis effect (peaks in 4 hours).
Thiazide diuretic.
It inhibits resorption of sodium and chloride at the distal convoluted tubule. Also enhance effects of other antihypertensives.
- Hyperglycemia
- Glycosuria
- Hyperuricaemia
- Hyponatremia
- Anorexia
- Impotence
- Postural hypotension
- Gastric irritation
- Nausea
- Vomiting
- Diarrhoea
- Hypokalemia
- Fatigue
- Orthostatic hypotension
- Hypersensitivity to sulfonamides
- Severe renal failure
- Severe hepatic failure
- Hypokalemia
- Anuria
- Amikacin
- Lithium
- Erythromycin
- Halofantrine
- Pentamidine
- Terfenadine
- Mannitol
Drug Status
| Availability | Prescription only |
| Pregnancy | Category B; Not recommended |
| Breastfeeding | Avoid use of >50mg/day |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Hydrochlorothiazide | 25mg | Tablet | 100’s | Dawa Ltd | Dawa Ltd |
| Hydrochlorothiazide | 50mg | Tablet | 100’s | Cosmos Ltd | Cosmos Ltd |
| Hydrochlorothiazide | 25mg | Tablet | 100’s | Cosmos Ltd | Cosmos Ltd |
| Hymet | 50mg | Tablet | 100’s | Laboratory & Allied | Laboratory & Allied |