- Prophylaxis & treatment of angina:
- Immediate release: 60mg TDS. Max 360mg/day
- XR: 120-480mg OD. Max 540mg/day
- Hypertension:
- 120-480mg OD/BD. Max 540mg/day for XR and360mg/day for controlled release
CR tablet: 90mg, 120mg, 180mg
SR tablet: 60mg
Capsule: 200mg, 300mg
SR capsule: 300mg
To be taken before meals and at bedtime
Non-dihydropyridine calcium channel blocker
It inhibits calcium ion influx into vascular smooth muscle and myocardium, relaxing smooth muscle, decreasing peripheral vascular resistance, dilating coronary arteries and prolonging AV node refractory period (class IV antiarrhythmic)
- Peripheral edema
- Headache
- Dizziness
- AV block
- Bradyarrhythmia
- Hypotension
- Flushing
- Vasodilation
- Fatigue
- Constipation
- Bronchitis
- Hypersensitivity to components
- Sick sinus syndrome without pacemaker
- SBP<90
- Acute MI with pulmonary congestion
- Bradycardia
- Porphyria
- AV and SA block
- Heart failure
- Cisapride
- Thioridazine
- Isocarboxazid
- Dantrolene
Angizem (Sun Pharma), Bi-tildiem (Sanofi), Calzem SR (Efroze), Dazil (Aegis), Dilcontin XL (Modi-Mundipharma), Diltan SR (Mepah), Diltiazem SR (distributed By Metro), Mono-Tildiem (Sanofi), Tildiem (Sanofi)
Drug Status
| Availability | Prescription only |
| Pregnancy | Category C |
| Breastfeeding | Use with caution |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Dilcontin XL | 90mg | Tablet | 100’s | Modi Mundipharma | Europa Healthcare |
| Dilcontin XL | 120 mg | Tablet | 100’s | Modi Mundipharma | Europa Healthcare |
| Dilcontin XL | 180mg | Tablet | 100’s | Modi Mundipharma | Europa Healthcare |
| Diltigesic | 2% w/w | Gel | 30g | Troikaa | Harley’s Ltd |
| Mono-Tildiem SR | 200mg | Capsule | 28’s | Sanofi-Aventis | Ressourcethica Kenya |