- Hypertension:
- Initially 2.5mg/6.25mg OD
- Max: 10mg/6.25mg/day
- Taper dose over 1 week to discontinue
Tablet:
- 2.5mg/6.25mg
- 5mg/6.25mg
- 10mg/6.25mg
- Taken in the morning before breakfast
- If withdrawn prior to surgery, at least 48 hours should be allowed between last dose and anesthesia.
- Therapy discontinuation should be gradual and patients advised to limit their physical activity during this period.
- Discontinue immediately in patients with ischemic heart disease.
- Do not administer calcium channel blockers and anti-arrhythmic agents IV during bisoprolol therapy.
Bisoprolol: Beta 1 selective beta-adrenoceptor antagonist
Hydrochlorothiazide: Thiazide diuretic
- Fatigue
- Headache
- Diarrhea
- Insomnia
- Impotence
- Bradycardia
- Hypokalemia
- Hypomagnesemia
- Hyperuricemia
- Hypotension
- Rash
- Photosensitivity
- Dizziness
- Asthenia
- Hyperglycemia
- Hypersensitivity to either component or sulfonamide derivatives
- Anuria
- Cardiogenic shock
- Heart block 2°/3°
- Overt cardiac failure
- Marked sinus bradycardia
- Dofetilide
- Isocarboxazid
Drug Status
| Availability | Prescription only |
| Pregnancy | Contraindicated |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Bisocard 5H | 5mg/6.25mg | Tablet | 30’s | Galaxy Pharma | Galaxy Pharma |
| Bisocard 10H | 10mg/6.25mg | Tablet | 30’s | Galaxy Pharma | Galaxy Pharma |
| Bisolol 5H | 5mg/6.25mg | Tablet | 30’s | Cadila Pharma | Cadila Pharma |
| Bisolol 10H | 10mg/6.25mg | Tablet | 30’s | Cadila Pharma | Cadila Pharma |