- Hypertension:
- 25-50mg daily. Full effect seen within 1-2 weeks.
- Angina pectoris:
- 50-100mg daily in a single or divided dose.
- Arrhythmias:
- After control with intravenous atenolol, oral dose for maintenance is 50-100mg daily
- MI:
- 5mg given by slow intravenous injection at a rate of 1mg per minute
- Followed after 15 minutes with 50mg by mouth,
- Then 50 mg after 12 hours
- Then (by mouth) 100 mg after 12 hours
- Then (by mouth) 100 mg once daily
- Migraine(off-label):
- 50-200mg daily in single or divided doses
- Mask symptoms of thyrotoxicosis (Off-label) :
- 25-100 mg PO once daily / BD
Tablet:
- 25mg
- 50mg
- 100mg
- Taken without regard to food.
- Avoid drinking apple/orange juice within 4 hours of administration.
- Abrupt withdrawal may cause ischaemic heart failure or MI.
- With long term beta blocker therapy, dosages should be reduced gradually over 1-2 weeks.
- For treatment of MI, it should be given within 12 hours of onset of chest pain.
- For intravenous infusion, give intermittently in Glucose 5% or Sodium chloride 0.9%. Suggested infusion time is 20 minutes.
Cardio-selective beta blocker.
It works by blocking the effects of the hormone epinephrine/adrenaline causing the heart to beat more slowly and with less force, which lowers blood pressure. It also helps widen veins and arteries to improve blood flow.
- Tiredness
- Hypotension
- Bradycardia
- Dizziness
- Drowsiness
- Drying of eyes, mouth and throat
- Heart failure
- Heart block
- Bronchospasm
- Sexual impotence
- Patients with bronchospasms, asthma or with a history of obstructive airway disease.
- Metabolic acidosis
- Second or third degree heart block
- Uncompensated heart failure
- Sinus bradycardia
- Phaeochromocytoma
- Pulmonary edema
- Hypersensitivity to components
- Cardiogenic shock
- Hypotension
- Severe peripheral arterial disease
CAUTION:
- Mask symptoms of hypoglycemia & hyperthyroidism
- Mask myasthenia gravis
- May aggravate psoriasis
- Abrupt withdrawal can cause angina, MI, arrhythmias and death
- NSAIDs
- Insulin
- Oral hypoglycemics
- Colestyramine
Drug Status
Availability | Prescription only |
Pregnancy | Category D; Contraindicated |
Breastfeeding | Contraindicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Anolol | 100mg | Tablet | 30’s | Zest Pharma | Synermed Pharma |
Anolol | 50mg | Tablet | 30’s | Zest Pharma | Synermed Pharma |
Atecard | 50mg | Tablet | 140’s | Alembic Pharma | Europa Healthcare |
Atecard | 100mg | Tablet | 140’s | Alembic Pharma | Europa Healthcare |
Atenol | 25mg | Tablet | 30’s | Galaxy Pharma | Galaxy Pharma |
Atenol | 50mg | Tablet | 30’s | Galaxy Pharma | Galaxy Pharma |
Atenol | 100mg | Tablet | 30’s | Galaxy Pharma | Galaxy Pharma |
Atenolol Denk | 50mg | Tablet | 100’s | Denk Pharma | Laborex Kenya |
Atin | 50mg | Tablet | 100’s | Jayson Pharma | Jayson Pharma |
Blokium | 50mg | Tablet | 30’s | Almirall | Harley’s Ltd |
Blokium | 100mg | Tablet | 30’s | Almirall | Harley’s Ltd |
Cardinol | 25mg | Tablet | 28’s | Cosmos Ltd | Cosmos Ltd |
Cardinol | 50mg | Tablet | 28’s | Cosmos Ltd | Cosmos Ltd |
Cardinol | 100mg | Tablet | 28’s | Cosmos Ltd | Cosmos Ltd |
Lonet 50 | 50 mg | Tablet | 100’s | Beximco Pharma | Madawa Pharma |
Tenormin | 50mg | Tablet | 28’s | AstraZeneca | Imperial Managed |
Tenormin | 100mg | Tablet | 28’s | AstraZeneca | Imperial Managed |
Tredol | 50mg | Tablet | 20’s | Delorbis Pharma | Europa Healthcare |
Tredol | 100mg | Tablet | 20’s | Delorbis Pharma | Europa Healthcare |