- Treatment and prevention of osteoporosis in postmenopausal women:
- PO 150mg every month OR IV 3mg every 3 months administered over 15-30 seconds
Tablet: 150mg
- Give with water 60min before first food/drink/drug
- Avoid lying down for 60min
- Calcium and vitamin D supplementation recommended if inadequate dietary intake
- Avoid invasive dental procedure
Bisphosphonate
It inhibits osteoclast activity, reducing bone resorption and turnover.
- Arthralgia
- Influenza
- Back pain
- Hypertension
- Abdominal pain
- Influenza-like symptoms
- Hypercholesterolemia
- Dyspepsia
- Nausea
- Constipation
- Headache
- URI
- UTI
- Dizziness
- Fatigue
- Rash
- Diarrhea
- Extremity pain
- Gastritis
- Myalgia
- Insomnia
- Depression
- Localized osteoarthritis
- Muscle cramps
- Hypersensitivity; anaphylaxis reported, including fatalities
- Uncorrected hypocalcemia
- Inability to stand or sit upright for at least 60 min
- Esophagus abnormalities that delay emptying (e.g, stricture, achalasia)
- CrCl <30
- Invasive dental procedure (IV use)
- Recombinant human parathyroid hormone
Drug Status
Availability | Prescription only |
Pregnancy | Not indicated |
Breastfeeding | Not indicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Baron | 150mg | Tablet | 1’s | Dawa Ltd | Dawa Ltd |
Bondronat | 6mg/6mL | Injection | 1’s | F. Hoffman-La Roche | Surgipharm Ltd |
Bonviva | 3mg/3mL | Pre-Filled Syringe | 1’s | F. Hoffman-La Roche | Surgipharm Ltd |
Bonviva | 150mg | Tablet | 1’s | F. Hoffman-La Roche | Surgipharm Ltd |
Cadronate | 150mg | Tablet | 3’s | Galaxy Pharma | Galaxy Pharma |