• Topical protectant for dry, itchy, or irritated skin
  • Barrier protection in diaper rash, eczema, contact dermatitis
  • Cosmetic uses: skin moisturizers, hair conditioners, makeup
  • Anti-foaming agent in simethicone for bloating/gas (oral form)

Dosage:

  • Topical: Apply thinly to affected area 1–3 times daily, or as directed
  • Oral (simethicone formulations): Typically 40–125 mg after meals and at bedtime

Varies by formulation:

  • Skin creams/lotions: 1%–10% dimethicone
  • Diaper creams/barrier ointments: up to 20%
  • Oral simethicone: 40–125 mg (dimethicone as part of simethicone
  • Topical: Clean and dry the affected area before applying. Use regularly for skin protection.
  • Avoid contact with eyes
  • Oral simethicone (anti-gas): Chew tablets thoroughly or use liquid as directed
  • Dimethicone is a silicone-based polymer that forms a protective barrier on the skin to reduce water loss and shield irritants
  • In oral form, it reduces surface tension, breaking up gas bubbles in the GI tract (simethicone effect)
  • Topical:
  • Generally well tolerated
  • Rare: Mild skin irritation or allergic reaction
  • Oral (simethicone):
    • Rare and mild GI upset (rarely reported)
  • Known hypersensitivity to dimethicone or formulation ingredients
  • None significant reported with topical or oral use

                                   Drug Status

Availability
Pregnancy
Breastfeeding
Schedule
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Dentinox Infant Colic Drops 42mg/5mL Oral Drops 100mL DDD Limited Harley’s Ltd
Infacol 40mg/mL Suspension 100 D Forest Labs Europa Healthcare