- HIV infection:
- >35kg: 1 tab OD
- Used in combination with other ARTs
Tablet: 300mg/300mg
Taken without regards to meals
Tenofovir: (NRTI); Analog of adenosine 5′-monophosphate that inhibits HIV-1 reverse transcriptase by competing with AMP as substrate, which results in the inhibition of viral replication
Lamivudine: Nucleoside Reverse Transcriptase Inhibitor (NRTI); Following phosphorylation, inhibits HIV reverse transcriptase by viral DNA chain termination
- Rash
- Hypercholesterolemia
- Headache
- Pain
- Elevated CK
- Diarrhea
- Depression
- Hyperamylasemia
- Back pain
- Fever
- Nausea
- Vomiting
- Abdominal pain
- Hematuria
- Anxiety
- Asthenia
- Pneumonia
- Elevated LFTs
- Arthralgia
- Myalgia
- Insomnia
- Dyspepsia
- Dizziness
- Neutropenia
- Bone density loss
- Lipodystrophy
- Fatigue
- Abnormal dreams
- URI
- Cough
- Neuropathy
- Glycosuria
- Musculoskeletal pain
- Anorexia
- Pruritus
- Increased Cr
- Hypersensitivity to class/components
- Recent or concurrent nephrotoxic agent use
WARNING
Severe acute exacerbations of hepatitis B reported in patients coinfected with HBV and HIV-1 and who have discontinued lamivudine or tenofovir df
- Elvitegravir/cobicistat/emtricitabine/tenofovir df
- Emtricitabine
- Cidofovir
Drug Status
Availability | Prescription only |
Pregnancy | Category C |
Breastfeeding | Nursing contraindicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Lamivudine/Tenofovir DF | 300mg/300mg | Tablet | 30’s | Macleods Pharma | Sai Pharma |
Telariv | 300mg/300mg | Tablet | 30’s | Cosmos Ltd | Cosmos Ltd |
Tenofovir/Lamivudine | 300mg/300mg | Tablet | 30’s | Mylan Labs C/O Surgilinks Ltd | Surgilinks Ltd |
Tenofovir and Lamivudine | 300mg/300mg | Tablet | 30’s | Hetero Labs | Unisel Ltd |
Tenofovir/Lamivudine | 300mg/300mg | Tablet | 30’s | Mylan Labs C/O Surgilinks Ltd | Surgilinks Ltd |