- HIV 1 infection in pregnant and treatment-naïve patients:
- Adults: PO 25mg OD
- 12-17 years (weight ≥35 kg): PO 25mg OD
Tablet: 25mg
- To be taken after meals
- If coadministered with antacids should only be administered either at least 2 hours before or at least 4 hours after rilpivirine
Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
It inhibits reverse transcriptase and incorporates into viral DNA resulting in DNA chain termination
- Elevated ALT /AST
- Hypercholesterolemia
- Somnolence (peds patients)
- Nausea (peds patients)
- Dizziness (peds patients)
- Vomiting (peds patients)
- Elevated Cr
- Hyperbilirubinemia
- Depression
- Rash
- Insomnia
- Headache
- Abdominal pain
- Fatigue
- Abnormal dreams
- Hypertriglyceridemia
- Lipodystrophy
- Hypersensitivity to components
- Breastfeeding
- Drugs that increase gastric pH
- Carbamazepine
- Dexamethasone
- Dexlansoprazole
- Efavirenz
- Elvitegravir/cobicistat/emtricitabine/tenofovir
- Eslicarbazepine acetate
- Esomeprazole
- Etravirine
- Fosphenytoin
- Lansoprazole
- Nevirapine
- Omeprazole
- Oxcarbazepine
- Pantoprazole
- Phenobarbital
- Phenytoin
- Rabeprazole
- Rifampin
- Rifapentine
- Vonoprazan
Drug Status
| Availability | Prescription only |
| Pregnancy | Can be used |
| Breastfeeding | Can be used |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Edurant | 25mg | Tablet | 30’s | Janssen-Cilag | Phillips Therapeutics |