- HIV infection:
- 50mg OD/BD
Tablet: 50mg
Taken without regards to meals
Integrase strand transfer inhibitor (INSTI)
It inhibits HIV integrase preventing viral DNA insertion into host cell DNA
- Elevated CK
- Hyperlipasemia
- Elevated LFTs
- Hyperglycemia
- Neutropenia
- Hyperbilirubinemia
- Insomnia
- Fatigue
- Headache
- Diarrhea
- Hypercholesterolemia
- Weight gain
- Anxiety
- Increased Cr
- Hypersensitivity to class/components
- Breastfeeding
- Dofetilide
Drug Status
| Availability | Prescription only |
| Pregnancy | Can be used |
| Breastfeeding | B/feeding contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Dolutegravir | 50mg | Tablet | 30’s | Hetero Labs | Unisel Ltd |
| Dolutegravir | 50mg | Tablet | 30’s | Laurus Labs | Medisel Kenya |
| Dolutegravir | 50mg | Tablet | 30’s | Aurobindo Pharma | Simba Pharma |
| Instgra | 50mg | Tablet | 30’s | Emcure Pharma | Lazor Pharma |
| Tivicay | 50mg | Tablet | 30’s | GSK Ltd | GSK Ltd |