- HIV infection:
- PO 1 tab OD
- Tablet:
- 300mg/100mg
- To be taken with food
Protease inhibitors
Bind to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles.
- Stomach ache
- Diarrhoea
- Nausea
- Vomiting
- Flushing
- Headache
- Dizziness
- Pain in the throat
- Cough
- Upset stomach
- A tingling sensation or numbness in the hands, feet or around the lips and mouth
- Bad taste in the mouth
- Damage to the nerves that can cause weakness and pain
- Itching
- Rash
- Joint pain and back pain
- Dyspepsia (indigestion)
- Fatigue
- Hepatic disease
- Hemophilia
- Erectile dysfunction
- Diabetes
- Gall bladder disease
- Kidney disease
- Astemizole
- Terfenadine
- Amiodarone
- Bepridil
- Dronedarone
- Flecainide
- Propafenone
- Quinidine
- Ergotamine
- Ergonovine
- Diazepam
- Estazolam
- Flurazepam
- Triazolam
- Midazolam
- Clozapine
- Pimozide
- Quetiapine
- Lurasidone
- Ranolazine
- Pethidine
- Buprenorphine
- Propoxyphene
- Cisapride
- Rifabutin
- Voriconazole
- Atorvastatin
- Lomitapide
- Rosuvastatin
- Irinotecan
- Alfuzosin
- Fusidic acid
- Sildenafil
- Avanafil
- Vardenafil
- Tadalafil
- Colchicine
- Salmeterol
- Warfarin
- Diltiazem
- Lidocaine
- Verapamil
- Digoxin
- Ethinylestradiol
- Cyclosporine
- Tacrolimus
- Sirolimus
- Piroxicam
Drug Status
| Availability | Prescription only |
| Pregnancy | Weigh risk vs benefit |
| Breastfeeding | Contraindicated |
| Schedule | Not scheduled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Anzavir-R | 300mg/100mg | Tablet | 30’s | Mylan Labs C/O Surgilinks | Surgilinks Ltd |
| Atazor-R | 300mg/100mg | Tablet | 30’s | Emcure Pharma | Lazor Pharma |