- Toxoplasmosis:
- Primary prophylaxis (Off-label): PO 50-75mg weekly
- Not 1st-line agent
- Given with dapsone, leucovorin
- Primary prophylaxis (Off-label): PO 50-75mg weekly
-
- Treatment:
- <60kg: PO 200mg *1, then 50mg OD for at least 6 weeks
- Given with sulfadiazine and leucovorin or clindamycin and leucovorin
- <60kg: PO 200mg *1, then 50mg OD for at least 6 weeks
- Treatment:
-
-
- >60kg: PO 200mg *1, then 75mg OD for at least 6 weeks
- Given with sulfadiazine and leucovorin or clindamycin and leucovorin
- >60kg: PO 200mg *1, then 75mg OD for at least 6 weeks
-
-
-
- Children >2 months old: Loading dose: PO 2mg/kg/d divided BD *3/7
- Maintenance: 1 mg/kg OD *4/52
- Children >2 months old: Loading dose: PO 2mg/kg/d divided BD *3/7
-
-
- Maintenance: (Off-label):
- <60kg: PO 25mg OD
- >60kg: PO 50mg OD
- Maintenance: (Off-label):
- Congenital toxoplasmosis (>2 months):
- Loading dose: 2mg/kg/day divided BD *2/7
- Maintenance: 1mg/kg OD for 2-6 months old then remainder of 12 months old 1mg/kg 3 times/week
- PCP prophylaxis (Off-label):
- PO 50-75mg weekly
- PO 50-75mg weekly
- Cystoisosporiasis (Off-label):
- Acute infection treatment
- PO 50-75mg OD
- Not 1st-line agent
- Give with leucovorin
- Acute infection treatment
- Chronic maintenance therapy:
- PO 25mg OD
- Not 1st-line agent
- Give with leucovorin
Tablet: 25mg
- To be taken with meals
- Take with a lot of water if taking with a drug with a sulfa component
Antiparasitic
It selectively inhibits plasmodial dihydrofolate reductase
- Vomiting
- Anorexia
- Abdominal cramps
- Dizziness
- Malaise
- Diarrhea
- Rash
- Abnormal skin pigmentation
- Pallor
- Purpura
- Glossitis
- Xerostomia
- Sore throat
- Hematuria
- Photosensitivity
- Hypersensitivity
- Megaloblastic or folate-deficiency anemia
- Dofetilide
- Eliglustat
Drug Status
Availability | Prescription only |
Pregnancy | Category C |
Breastfeeding | Contraindicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Column 1 Value | Column 2 Value | Column 3 Value | Column 4 Value | Column 5 Value | Column 6 Value |