- Diarrhoea due to giardia lambia or C.parvum
- Amoebiasis & helminthic infections.
Dosing:
-
- Adult: 500mg BD * 3/7
- 4-11 years: 200mg BD *3/7
- 1-3 years: 100mg BD *3/7
Tablet: 500mg, 200mg
Suspension: 100mg/5mL
- Tablet safety not established in children < 12 years, therefore suspension best option for children < 12 years.
Thiazolide antiprotozoal.
Interferes with pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction essential to anaerobic energy metabolism.
Well tolerated.
- Metallic taste
- Asthenia
- Fever
- Hypersensitivity reactions
- Discoloured urine
- Headache
- Abdominal pain
- Nausea
- Hypersensitivity to components
- Children < 1 year.
- Immunodeficient patients
- Warfarin
- Phenytoin
- Valproic acid
Drug Status
| Availability | Prescription or OTC |
| Pregnancy | Category B3; Contraindicated |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Netazox | 500mg | Tablet | 6’s | Ind-Swift Ltd | Ind-Swift Ltd |
| Netazox | 100mg/5mL | Suspension | 30mL | Ind-Swift Ltd | Ind-Swift Ltd |
| Netazox DT | 200mg | Orodispersible tablet | 6’s | Ind-Swift Ltd | Ind-Swift Ltd |
| Nidozox | 100mg/5mL | Suspension | 30mL, 60mL | The ACME Labs | Highridge Pharma |
| Nizal | 500mg | Tablet | 10’s | Coral Labs | Lords Healthcare |
| Nizal | 100mg/5mL | Suspension | 30mL | Coral Labs | Lords Healthcare |