- Post-menopausal breast cancer:
- 5mg OD
- Adjuvant treatment of early breast cancer
- For those who have received 5 years of adjuvant tamoxifen therapy
- Locally advanced or metastatic breast cancer
- Advanced breast cancer with disease progression following anti-estrogen therapy
- 5mg OD
- Ovulation induction(Off-label):
- 2.5-5mg OD *5/7
- Start on day 3 of menstrual cycle
- 2.5-5mg OD *5/7
Tablet: 2.5mg
None remarkable
Aromatase inhibitor
It blocks the enzymatic androgen conversion to estrogen by binding to the heme group of aromatase enzyme, reducing hormone receptor positive cancer cell growth
- Hot flashes
- Arthralgia
- Flushing
- Asthenia
- Edema
- Headache
- Dizziness
- Hypercholesterolemia
- Diaphoresis
- Bone pain
- Musculoskeletal pain
- Dyspnea
- Fatigue
- Fractures
- Night sweats
- Cough
- Weight gain
- Constipation
- Nausea
- Hypersensitivity to drug or components
- Pregnancy
- Premenopausal women
- Breastfeeding during treatment and for at least 3 weeks after discontinuation
- DHEA
- Estrogen
- Ethinylestradiol
- Tamoxifen
Drug Status
| Availability | Prescription only |
| Pregnancy | Category D |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Femara | 2.5mg | Tablet | 30’s | Novartis Pharma | Novartis Kenya |
| Fertizol | 2.5mg | Tablet | 28’s | Galaxy Pharma | Galaxy Pharma |
| Glotraz | 2.5mg | Tablet | 30’s | Globela Pharma | Nila Pharma |
| Let-Life | 2.5mg | Tablet | 20’s | Innocia Lifesciences | Wessex Pharma |
| Letero | 2.5mg | Tablet | 30’s | Hetero Labs | Unisel Ltd |
| Letrofem | 2.5mg | Tablet | 30’s | Innocia Lifesciences | Wessex Pharma |
| Letrol | 2.5mg | Tablet | 5’s | Renata Limited | Harley’s Ltd |
| Letroz | 2.5mg | Tablet | 25’s | Sun Pharma | Sun Pharma |
| Letrozole | 2.5mg | Tablet | 30’s | Novartis Kenya | Novartis Kenya |
| Mamazol | 2.5mg | Tablet | 30’s | Khandelwal Labs | PSM Pharma |