• Seasonal allergic rhinitis (hay fever) with nasal congestion
  • Relieves symptoms such as sneezing, runny nose, itchy eyes, and nasal congestion

Dosage (Adults and adolescents ≥12 years):

  • Fexofenadine 60 mg + Pseudoephedrine 120 mg (extended-release):
    • Take 1 tablet twice daily (every 12 hours)
  • Fexofenadine 180 mg + Pseudoephedrine 240 mg (extended-release):
    • Take 1 tablet OD
  • Fexofenadine 60 mg + Pseudoephedrine 120 mg (12-hour release)
  • Fexofenadine 180 mg + Pseudoephedrine 240 mg (24-hour release)
  • Take with water; avoid taking with fruit juices (e.g., grapefruit, orange, apple) as they may decrease fexofenadine absorption
  • Do not crush or chew extended-release tablets
  • Avoid taking close to bedtime (pseudoephedrine may cause insomnia)
  • Fexofenadine: Second-generation H1 antihistamine with minimal sedation; blocks histamine receptors in peripheral tissues
  • Pseudoephedrine: Alpha-adrenergic agonist; causes vasoconstriction in nasal mucosa, relieving congestion
  • Together, they offer comprehensive allergy symptom relief, including nasal decongestion.

Fexofenadine:

  • Headache
  • Drowsiness (rare)
  • Nausea
  • Dizziness

Pseudoephedrine:

  • Nervousness
  • Restlessness
  • Insomnia
  • Increased heart rate
  • Elevated blood pressure

Combination:

  • Additive CNS stimulation possible (especially in sensitive individuals)
  • Severe hypertension
  • Coronary artery disease
  • Hyperthyroidism
  • Narrow-angle glaucoma
  • Urinary retention
  • Use of MAO inhibitors within the last 14 days
  • MAO inhibitors: Risk of hypertensive crisis
  • Fruit juices: Decrease fexofenadine absorption
  • CNS stimulants or decongestants: Additive effects with pseudoephedrine
  • Beta-blockers: May potentiate hypertensive effect

                                   Drug Status

Availability
Pregnancy
Breastfeeding
Schedule
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Fexet D 120mg/60mg Tablet 10’s Getz Pharma Surgipharm Ltd