• GI and GUT smooth muscle spasms
  • Biliary and renal colics
    • 40-80mg TDS

Tablet:

  • 40mg
  • 80mg

Injection:

  • 20mg/mL

To be taken without regard to food.

Selective phosphodiesterase-4 (PDE4) inhibitor. Antispasmodic.

PDE4 is responsible for degradation of cAMP. Inhibition of PDE4 leads to increased levels of cAMP and consequently smooth muscle relaxation. Drotaverine has no anticholinergic effects.

  • Dizziness
  • Nausea
  • Headache
  • Allergic reactions
  • Nausea
  • Vomiting
  • Drop in BP
  • Hypersensitivity to components
  • Intestinal obstruction
  • Faecal impaction
  • Colonic atony
  • Severe renal or hepatic impairment
  • Atropine
  • Levodopa
  • Diazepam
  • Diclofenac

                                   Drug Status

Availability Prescription only
Pregnancy Contraindicated
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Droverine 40mg Tablet 100’s Innocia Lifesciences Wessex Pharma
No-Spa 40mg/2mL Injection 25’s Sanofi-Aventis Ressourcethica Kenya
No-Spa 40mg Tablet 20’s, 100’s Sanofi-Aventis Ressourcethica Kenya
No-Spa Forte 80mg Tablet 20’s Sanofi-Aventis Ressourcethica Kenya
Spacovin 20mg/mL Injection 5’s M.J. Biopharm Europa Healthcare
Spasmocare 80mg Tablet 30’s Medisel Kenya Medisel Kenya