- Motion sickness:
- Adults and > 12 years:
- PO/IV/IM 50mg every 4-6 hours
- Max 400mg/day
- Adults and > 12 years:
-
- 2-6 years:
- PO 12.5-25mg TDS/QID
- Max 75mg/day
- 2-6 years:
-
- 6-11 years:
- PO 12.5-25mg TDS/QID
- Max 150mg/day
- 6-11 years:
Tablet: 50mg
Suspension: 12.5mg/5mL
- Given 30 min-1 hour before travel
H1 receptor antagonist
It non-selectively antagonizes central and peripheral histamine H1 receptors.It also antagonizes cholinergic receptors producing antiemetic effects
- Drowsiness
- Dizziness
- Impaired coordination
- Headache
- Epigastric discomfort
- Thickened bronchial secretions
- Dry mucous membranes
- Paradoxical CNS stimulation
- Constipation
- Dysuria
- Urinary retention
- Hypotension
- Blurred vision
- Diplopia
- Palpitations
- Tachycardia
- Photosensitivity
- Diaphoresis
- Erectile dysfunction
- Documented hypersensitivity to dimenhydrinate or diphenhydramine
- Preemies and neonates (<2 years)
- Nursing women
- Potassium salts
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Category B; Can be used |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Gravinate | 12.5mg/4mL | Suspension | 60mL | The Searle Company | Globe Pharmacy |
| Gravinate | 50mg | Tablet | 100’s | The Searle Company | Globe Pharmacy |