- Allergic rhinitis (seasonal and perennial)
- Chronic idiopathic urticaria (hives)
Typical Adult Dosage:
- OD 20 mg
Pediatric Use:
- Children ≥6 years and ≥20 kg: 10 mg OD(oral solution or chewable tablets available)
- PO: 20 mg
- Oral solution/chewable tablets: Pediatric-friendly formulations (commonly 10 mg)
- Take on an empty stomach (1 hour before or 2 hours after meals) for optimal absorption
- Do not take with fruit juice (apple, grapefruit, orange) as it may reduce bioavailability
- Swallow with water
- Class: Second-generation, non-sedating H1-antihistamine
- Mechanism: Selectively blocks peripheral H1 receptors to inhibit histamine-mediated symptoms like sneezing, itching, runny nose, and hives
- Onset of action: Within 1 hour
- Duration: ≥24 hours
- Headache
- Drowsiness (rare)
- Dizziness
- Abdominal pain or GI upset
- Fatigue
Note: Has a low incidence of sedation compared to other antihistamines
- Hypersensitivity to bilastine or any of its components
- Use caution in patients with renal impairment (especially if co-administered with P-glycoprotein inhibitors like ketoconazole, erythromycin)
- Fruit juice: Reduces absorption
- P-gp inhibitors (e.g., cyclosporine, ritonavir, ketoconazole): May increase bilastine plasma concentration
- No major CYP450 enzyme interactions
Drug Status
Availability | |
Pregnancy | |
Breastfeeding | |
Schedule |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Ilaxten | 20mg | Tablet | 4’s, 10’s | Menarini International | Phillips Therapeutics |