- Type 2 DM:
- PO 5mg/ 500mg OR 12.5mg/ 500mg BD with meals
- Max 25mg/2000mg per day
Tablet:
- 5mg/ 500mg
- 5mg/ 1000mg
- 12.5mg/ 500mg
- 12.5mg/ 1000mg
- Take orally twice daily with meals to minimize gastrointestinal side effects (from metformin).
- Ensure adequate hydration to avoid dehydration, a common side effect of empagliflozin
- Empagliflozin (SGLT2 Inhibitor): It reduces glucose reabsorption by the kidneys, increasing urinary glucose excretion and lowering blood glucose levels.
- Metformin (Biguanide): It reduces hepatic glucose production, decreases intestinal glucose absorption, and improves insulin sensitivity.
- Gastrointestinal disturbances (e.g, nausea, diarrhea, abdominal pain)
- Risk of lactic acidosis
- Increased urination
- UTI
- Genital infections
- Dehydration
- Lactic acidosis
- Ketoacidosis
- Hypoglycemia
- Acute kidney injury
- Hypotension
- Prednisolone
- Furosemide
- Baclofen
- Insulin
- Gliclazide
Drug Status
Availability | Prescription only |
Pregnancy | Not recommended |
Breastfeeding | Not recommended |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Coempaken | 12.5mg/1g | Tablet | 28’s | Pharmaken Ltd | Pharmaken Ltd |
Coempaken | 12.5mg/500mg | Tablet | 28’s | Pharmaken Ltd | Pharmaken Ltd |
Diajard-MXR | 12.5mg/1g | Tablet | 14’s | Innocia Lifesciences | Wessex Pharma |
Diajard-MXR | 5mg/1g | Tablet | 14’s | Innocia Lifesciences | Wessex Pharma |
Empa-M | 12.5mg/1g | Tablet | 14’s | Qpharma DMCC | Cintana Healthcare |
Empa-M | 12.5mg/500mg | Tablet | 14’s | Qpharma DMCC | Cintana Healthcare |
Empaflo-M | 12.5mg/500mg | Tablet | 30’s | Dawa Ltd | Dawa Ltd |
Empaflo-M | 12.5mg/1g | Tablet | 30’s | Dawa Ltd | Dawa Ltd |
Empiget M | 5mg/1g | Tablet | 28’s | Getz Pharma | Surgipharm Ltd |
Empiget M | 12.5mg/1g | Tablet | 14’s | Getz Pharma | Surgipharm Ltd |
Empiget M | 5mg/500mg | Tablet | 14’s | Getz Pharma | Surgipharm Ltd |
Glifempa M | 25mg/500mg | Tablet | 30’s | Galaxy Pharma | Galaxy Pharma |
Glifempa M | 10mg/500mg | Tablet | 30’s | Galaxy Pharma | Galaxy Pharma |
Synjardy | 5mg/1g | Tablet | 56’s | Boeheringer Ingelheim | Surgipharm Ltd |
Synjardy | 5mg/850mg | Tablet | 56’s | Boeheringer Ingelheim | Surgipharm Ltd |
Synjardy | 12.5mg/1g | Tablet | 56’s | Boeheringer Ingelheim | Surgipharm Ltd |
Synjardy | 12.5mg/850mg | Tablet | 56’s | Boeheringer Ingelheim | Surgipharm Ltd |
Xenglu-Met | 12.5mg/500mg | Tablet | 14’s | Hilton Pharma | Surgilinks Ltd |
Xenglu-Met | 12.5mg/1g | Tablet | 14’s | Hilton Pharma | Surgilinks Ltd |