Insulin lispro/ Insulin lispro protamine

Injection/Pre-filled syringe:

• 50/50 (50% insulin lispro protamine suspension and 50% insulin lispro)
• 75/25 (75% insulin lispro protamine suspension and 25% insulin lispro)

• Administer subcutaneously in the abdomen, thigh, upper arm or buttocks.
• Administer BD (ie, before breakfast and evening meal); each dose intended to cover 2 meals or a meal and snack
• Rotate injection sites to reduce the risk of lipodystrophy.
• Store unopened vials or pens in the refrigerator
• Once in use, they may be stored at room temperature.

Insulin lispro is a rapid-acting insulin analog. It lowers blood glucose by facilitating the uptake of glucose into skeletal muscle and fat and inhibiting hepatic glucose production. Its action begins rapidly after injection, making it suitable for mealtime control.

Insulin lispro protamine is an intermediate-acting insulin. It provides a longer, basal insulin action by forming a crystalline suspension with protamine, ensuring more extended blood glucose control throughout the day.

• Hypoglycemia
• Injection site rxn
• Injection site lipodystrophy
• Myalgia
• Pruritus
• Rash
• URI
• Weight gain
• Headache
• Peripheral edema
• Hypersensitivity rxn
• Influenza

• Hypersensitivity to insulin lispro, insulin lispro protamine, or any excipients in the formulation.
• Continuous SC infusion pump use
• Hypoglycemia
• IM/IV use

• Glucagon
• Macimorelin
• Repaglinide
• Rosiglitazone