• Type 2 DM especially for patients inadequately controlled on diet, exercise, and monotherapy with either gliclazide or metformin:
    • Initial dose: PO 4mg/ 500mg OD taken with the largest meal
    • Max: 320mg/2000mg per day

Tablet:

  • 40mg/500mg
  • 80mg/500mg
  • Take orally with meals to minimize GI side effects (metformin) and reduce the risk of hypoglycemia (gliclazide).
  • Gliclazide (Sulfonylurea): It stimulates insulin secretion from pancreatic beta cells, lowering blood glucose levels.
  • Metformin (Biguanide): It lowers glucose production in the liver, improves insulin sensitivity and reduces glucose absorption from the intestines.
  • Hypoglycaemia
  • Dizziness
  • Sweating
  • Palpitations
  • Hunger pangs
  • Dry mouth
  • Dry skin
  • Taste change
  • Nausea
  • Diarrhoea
  • Stomach pain
  • Headache
  • Severe renal impairment
  • Hypersensitivity to any of the formulation’s components.
  • Diabetic ketoacidosis
  • Type 1 DM
  • Vitamin B12 deficiency
  • Liver problems
  • Cardiovascular disease
  • Insulin
  • Hydrochlorothiazide
  • Amlodipine
  • Furosemide
  • Digoxin
  • Metoprolol
  • Prednisolone

                                   Drug Status

Availability Prescription only
Pregnancy Not recommended
Breastfeeding Not recommended
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Gliclaz M 80mg/500mg Tablet 10’s PSM Pharma PSM Pharma