- Menorrhagia:
- 1000mg TDS during menses. Max: 5 days
- Epistaxis:
- 1000-1500mg BD/TDS * 7/7
- Dental extraction in haemophiliacs:
- 1000-1500mg TDS. Based on 25mg/kg
- Hereditary angioedema (Off-label):
- 500-3000mg/day BD/TDS. Max: 1 g/dose
- Postpartum hemorrhage (Off-label):
- 1000 mg IV STAT; to be started within 3 hours of delivery. May be repeated once more.
- Conisation of the cervix (Off-label):
- 1500mg TDS
- Traumatic hyphaema (Off-label):
- 1000-1500mg TDS
- Tablet/Capsule:
- 250mg
- 500mg
- Injection:
- 100mg/mL
- Can be taken with or without food.
- To be swallowed whole without breaking or crushing.
Antifibrinolytic.
It is a competitive inhibitor of the activation of plasminogen to plasmin, decreasing plasmin formation and fibrinolysis.
- Headache
- Back pain
- Abdominal pain
- Musculoskeletal pain
- Arthralgia
- Muscle cramps
- Nausea
- Vomiting
- Diarrhoea
- Allergic skin reactions
- Migraine
- Dizziness
- Hypersensitivity to the components
- Severe renal impairment
- Active thromboembolic disease
- History of thromboembolism
- History of convulsions
- Subarachnoid hemorrhage (IV use)
- COCs
- Fibrinolytic preparations
Drug Status
Availability | Prescription or OTC |
Pregnancy | Category B1; Not recommended |
Breastfeeding | Unknown |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Hemsamic | 500mg | Capsule | 20’s | Tabros Pharma | Globe Pharmacy |
Hemsamic | 250mg | Injection | 5’s | Tabros Pharma | Globe Pharmacy |
Intrax | 100mg/mL | Injection | 5’s | Radiance Pharma | Radiance Pharma |
Menozip | 500mg | Tablet | 20’s | National Pharmacy | National Pharmacy |
Pause | 500mg | Tablet | 30’s | Emcure Pharma | Lazor Pharma |
Pause | 500mg/5mL | Injection | 5’s | Emcure Pharma | Lazor Pharma |
Plasminex | 100mg/mL | Injection | 10’s | PT Sanbe Farma | Sai Pharma |
Tafixyl | 500mg/5mL | Injection | 5’s | Pharma Bavaria | Goodman Agencies |
Tasemic | 500mg/5mL | Injection | 10’s | Tasa Pharma | Sai Pharma |
Texakind | 500mg/5mL | Injection | 4’s | Mankind Pharma | Pharma Specialities |
Transamin | 500mg/5mL | Injection | 10’s | Hilton Pharma C/O Surgilinks Ltd | Surgilinks Ltd |
Transamin | 250mg | Capsule | 100’s | Hilton Pharma C/O Surgilinks Ltd | Surgilinks Ltd |
Transamin | 500mg | Capsule | 20’s | Hilton Pharma C/O Surgilinks Ltd | Surgilinks Ltd |
Transic | 500mg | Injection | 10’s | Nabiqasim Industries | Harley’s Ltd |
Transic | 250mg | Injection | 10’s | Nabiqasim Industries | Harley’s Ltd |
Trantum | 500mg | Tablet | 20’s | Kusum Healthcare | Zawadi Healthcare |
Trenaxa | 500mg | Tablet | 30’s | Macleods Pharma | Sai Pharma |
Trenexa R | 500mg/5mL | Injection | 5’s | Orange Pharma | Reddys Pharma |
Unotation | 500mg/5mL | Injection | 5’s | Unosource Pharma | Unisel Ltd |