• Acute MI:
    • 18mg (10 units) IV bolus given over 2 minutes, then second dose given 30 minutes after first

Injection: 18mg/10mL

  • Stable for 4 hours at room temp

Thrombolytic

It binds to fibrin and converts tissue plasminogen to plasmin, promoting fibrinolysis

  • Bleeding
  • Hypersensitivity
  • Active bleeding
  • Recent CVA (within 3 months)
  • Recent intracranial or intraspinal surgery or trauma (within 3 months)
  • Intracranial neoplasm
  • AVM
  • Aneurysm
  • Bleeding diathesis
  • Severe uncontrolled hypertension
  • Mifepristone
  • Human prothrombin complex concentrate

                          Drug Status

Availability Prescription only
Pregnancy Category C
Breastfeeding Unlikely to be b/feeding at indicated circumstances
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Mirel 18mg/10mL Injection 1’s Galaxy Pharma Galaxy Pharma