- Stroke and systemic embolism in nonvalvular atrial fibrillation
- PO 5mg BD
- PO 5mg BD
- Postoperative prophylaxis of DVT/PE:
- Knee replacement surgery:
- PO 2.5mg BD *12/7
- Started 12-24 hours post-op
- Knee replacement surgery:
- Hip replacement surgery:
- PO 2.5mg BD *35/7
- Started 12-24 hours post-op
- DVT/PE:
- PO 10mg BD *1/52, then 5mg BD
- Tablet:
- 2.5mg
- 5mg
Taken without regards to meals
Anticoagulant
Selectively blocks active site of factor Xa, inhibiting blood coagulation
- Bleeding
- Anemia
- Nausea
- Severe hypersensitivity to components
- Active pathological bleeding
- Pregnancy
- Hepatic impairment
WARNING
- Premature treatment discontinuation causes an increase in thrombotic event risk
- Epidural/spinal hematoma risk after epidural/spinal anesthesia or spinal puncture in anticoagulated patients
- Betrixaban
- Carbamazepine
- Defibrotide
- Dexamethasone
- Fondaparinux
- Fosphenytoin
- Mifepristone
- Omacetaxine
- Phenytoin
- Human prothrombin complex concentrate
- Rifabutin
- Secobarbital
- Vorapaxar
Drug Status
Availability | Prescription only |
Pregnancy | Category B; Not recommended |
Breastfeeding | Contraindicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Apixa-Q | 2.5mg | Tablet | 14’s | Q Pharma DMCC | Cintana Healthcare |
Apixa-Q | 5mg | Tablet | 14’s | Q Pharma DMCC | Cintana Healthcare |
Apixaget | 2.5mg | Tablet | 30’s | Getz Pharma | Surgipharm Ltd |
Apixaget | 5mg | Tablet | 30’s | Getz Pharma | Surgipharm Ltd |
Eliquis | 2.5mg | Tablet | 20’s | Bristol Myers Squibb | Bristol Myers Squibb |
Eliquis | 5mg | Tablet | 20’s | Bristol Myers Squibb | Bristol Myers Squibb |
Pixab | 5mg | Tablet | 30’s | Pinnacle Lifescience | Tiba Healthcare |
Pixab | 2.5mg | Tablet | 30’s | Pinnacle Lifescience | Tiba Healthcare |