- Acute exacerbations of chronic bronchitis:
- PO 500mg BD OR 250mg QID (i.e, 1000mg/day)
- PO 500mg BD OR 250mg QID (i.e, 1000mg/day)
- Moderate-severe acne:
- Adults: PO 500mg BD OR 250mg QID (i.e, 1000mg/day)
- Adolescents: PO 250-500mg BD/QID *1-2 weeks, then 250-500mg OD
- Brucellosis:
- PO 500mg QID *3/52 accompanied by streptomycin IM 1g BD *1/52 then OD *1/52
- PO 500mg QID *3/52 accompanied by streptomycin IM 1g BD *1/52 then OD *1/52
- Syphilis in patients allergic to penicillin:
- Early syphilis (duration <1 year): PO 500mg QID *15/7
- Syphilis (duration >1 year [except neurosyphilis]): PO 500mg QID *1/12
- Gonorrhea:
- PO 500mg QID *1/52
- PO 500mg QID *1/52
- Uncomplicated urethral, endocervical or rectal infections caused by Chlamydia trachomatis
- PO 500mg QID *1/52
- PO 500mg QID *1/52
- Bacterial infections:
- Adults: PO 1-2 g/day PO divided BD/QID
- Children >8 years: PO 25-50mg/kg/day divided QID
- Max: 3g/day
Capsule: 250mg
- To be taken 1 hour before or 2 hours after meals
- To be taken with a lot of water to avoid esophageal irritation and ulceration
Tetracyclines
It inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s)
- Nausea
- Vomiting
- Diarrhea
- Epigastric discomfort
- Rash
- Urticaria
- Photosensitivity
- Elevated BUN
- Permanent tooth discoloration (patients <8 years)
- Reversible tooth discoloration (adult patients)
- Enamel hypoplasia
- Hypersensitivity to class/components
- Severe hepatic dysfunction
- Pregnancy
- Breastfeeding
- Patients <8 years
- Acitretin
- Flibanserin
- Lomitapide
- Lonafarnib
- Tretinoin
- Oral contraceptives
Drug Status
Availability | Prescription only |
Pregnancy | Category D |
Breastfeeding | Contraindicated |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Biotet | 250mg | Capsule | 1000’s | Biodeal Labs | Biodeal Labs |
Racycline | 250mg | Capsule | 100’s | Laboratory & Allied | Laboratory & Allied |
Tetraline | 250mg | Capsule | 100’s | Dinlas Pharma | Dinlas Pharma |